RT Journal Article T1 Wave Propagation in a Fractional Viscoelastic Tissue Model: Application to Transluminal Procedures A1 Gomez, Antonio A1 Rus, Guillermo A1 Saffari, Nader K1 Transluminal elastography K1 Shear wave K1 Fractional viscoelasticity K1 Kelvin voigt fractional derivative K1 Finite difference K1 Elastografía K1 Onda S K1 Elasticidad K1 Análisis de elementos finitos AB In this article, a wave propagation model is presented as the first step in the development of a new type of transluminal procedure for performing elastography. Elastography is a medical imaging modality for mapping the elastic properties of soft tissue. The wave propagation model is based on a Kelvin Voigt Fractional Derivative (KVFD) viscoelastic wave equation, and is numerically solved using a Finite Difference Time Domain (FDTD) method. Fractional rheological models, such as the KVFD, are particularly well suited to model the viscoelastic response of soft tissue in elastography. The transluminal procedure is based on the transmission and detection of shear waves through the luminal wall. Shear waves travelling through the tissue are perturbed after encountering areas of altered elasticity. These perturbations carry information of medical interest that can be extracted by solving the inverse problem. Scattering from prostate tumours is used as an example application to test the model. In silico results demonstrate that shear waves are satisfactorily transmitted through the luminal wall and that echoes, coming from reflected energy at the edges of an area of altered elasticity, which are feasibly detectable by using the transluminal approach. The model here presented provides a useful tool to establish the feasibility of transluminal procedures based on wave propagation and its interaction with the mechanical properties of the tissue outside the lumen. PB MDPI YR 2021 FD 2021-04-15 LK http://hdl.handle.net/10668/4134 UL http://hdl.handle.net/10668/4134 LA en NO Gomez A, Rus G, Saffari N. Wave Propagation in a Fractional Viscoelastic Tissue Model: Application to Transluminal Procedures. Sensors. 2021 Apr 15;21(8):2778 DS RISalud RD Apr 9, 2025