RT Journal Article
T1 Predictors of Loss of Functional Independence in Parkinson's Disease: Results from the COPPADIS Cohort at 2-Year Follow-Up and Comparison with a Control Group.
A1 Santos García, Diego
A1 de Deus Fonticoba, Teresa
A1 Cores Bartolomé, Carlos
A1 Naya Ríos, Lucía
A1 García Roca, Lucía
A1 Martínez Miró, Cristina
A1 Canfield, Hector
A1 Jesús, Silvia
A1 Aguilar, Miquel
A1 Pastor, Pau
A1 Cosgaya, Marina
A1 García Caldentey, Juan
A1 Caballol, Nuria
A1 Legarda, Inés
A1 Hernández Vara, Jorge
A1 Cabo, Iria
A1 López Manzanares, Lydia
A1 González Aramburu, Isabel
A1 Ávila Rivera, María A
A1 Gómez Mayordomo, Víctor
A1 Nogueira, Víctor
A1 Puente, Víctor
A1 Dotor, Julio
A1 Borrué, Carmen
A1 Solano Vila, Berta
A1 Álvarez Sauco, María
A1 Vela, Lydia
A1 Escalante, Sonia
A1 Cubo, Esther
A1 Carrillo Padilla, Francisco
A1 Martínez Castrillo, Juan C
A1 Sánchez Alonso, Pilar
A1 Alonso Losada, Maria G
A1 López Ariztegui, Nuria
A1 Gastón, Itziar
A1 Kulisevsky, Jaime
A1 Blázquez Estrada, Marta
A1 Seijo, Manuel
A1 Rúiz Martínez, Javier
A1 Valero, Caridad
A1 Kurtis, Mónica
A1 de Fábregues, Oriol
A1 González Ardura, Jessica
A1 Alonso Redondo, Ruben
A1 Ordás, Carlos
A1 López Díaz, Luis M
A1 McAfee, Darrian
A1 Martinez-Martin, Pablo
A1 Mir, Pablo
A1 Coppadis Study Group, 
K1 Parkinson’s disease
K1 activities of daily living
K1 dependency
K1 disability
K1 gait
AB The aim of this study was to compare the progression of independence in activities of daily living (ADL) in Parkinson's disease (PD) patients versus a control group, as well as to identify predictors of disability progression and functional dependency (FD). PD patients and control subjects, who were recruited from 35 centers of Spain from the COPPADIS cohort between January 2016 and November 2017 (V0), were included. Patients and subjects were then evaluated again at the 2-year follow-up (V2). Disability was assessed with the Schwab & England Activities of Daily Living Scale (S&E-ADLS) at V0 and V2. FD was defined as an S&E-ADLS score less than 80%. In the PD group, a significant decrease in the S&E-ADLS score from V0 to V2 (N = 507; from 88.58 ± 10.19 to 84.26 ± 13.38; p  In conclusion, autonomy for ADL worsens in PD patients compared to controls. Cognitive impairment, gait problems, fatigue, depressive symptoms, more advanced disease, and a non-tremor phenotype are independent predictors of FD in the short-term.
SN 2075-4418
YR 2021
FD 2021-09-29
LK https://hdl.handle.net/10668/27951
UL https://hdl.handle.net/10668/27951
LA en
DS RISalud
RD Apr 7, 2025