TY  - JOUR
AU  - Giraldo, E
AU  - Nebot, V J
AU  - Đorđević, S
AU  - Requejo-Aguilar, R
AU  - Alastrue-Agudo, A
AU  - Zagorodko, O
AU  - Armiñan, A
AU  - Martinez-Rojas, B
AU  - Vicent, M J
AU  - Moreno-Manzano, V
PY  - 2021
DO  - 10.1016/j.biomaterials.2021.121052
UR  - http://hdl.handle.net/10668/18369
T2  - Biomaterials
AB  - Rho/ROCK signaling induced after spinal cord injury (SCI) contributes to secondary damage by promoting apoptosis, inflammation, and axon growth inhibition. The specific Rho-kinase inhibitor fasudil can contribute to functional regeneration after SCI,...
LA  - en
PB  - Elsevier
KW  - Axonal elongation
KW  - Fasudil
KW  - Neuroprotection
KW  - Polymer therapeutics
KW  - Polymer-drug conjugates
KW  - RhoA/ROCK Inhibitor
KW  - Spinal cord injury
KW  - Animals
KW  - Neural stem cells
KW  - Polymers
KW  - Rats
KW  - Spinal cord injuries
KW  - rho-associated kinases
TI  - A rationally designed self-immolative linker enhances the synergism between a polymer-rock inhibitor conjugate and neural progenitor cells in the treatment of spinal cord injury.
TY  - research article
VL  - 276
ER  -