RT Journal Article
T1 COVID-19 anosmia and gustatory symptoms as a prognosis factor: a subanalysis of the HOPE COVID-19 (Health Outcome Predictive Evaluation for COVID-19) registry.
A1 Porta-Etessam, Jesús
A1 Núñez-Gil, Iván J
A1 González García, Nuria
A1 Fernandez-Perez, Cristina
A1 Viana-Llamas, María C
A1 Eid, Charbel Maroun
A1 Romero, Rodolfo
A1 Molina, María
A1 Uribarri, Aitor
A1 Becerra-Muñoz, Victor Manuel
A1 Aguado, Marcos García
A1 Huang, Jia
A1 Rondano, Elisa
A1 Cerrato, Enrico
A1 Alfonso, Emilio
A1 Mejía, Alex Fernando Castro
A1 Marin, Francisco
A1 Roubin, Sergio Raposeiras
A1 Pepe, Martino
A1 Feltes, Gisela
A1 Maté, Paloma
A1 Cortese, Bernardo
A1 Buzón, Luis
A1 Mendez, Jorge Játiva
A1 Estrada, Vicente
K1 Anosmia
K1 COVID-19
K1 Hospital
K1 Pathophysiology
K1 Prognosis
K1 SARS-COV-2
AB Olfactory and gustatory dysfunctions (OGD) are a frequent symptom of coronavirus disease 2019 (COVID-19). It has been proposed that the neuroinvasive potential of the novel SARS-CoV-2 could be due to olfactory bulb invasion, conversely studies suggest it could be a good prognostic factor. The aim of the current study was to investigate the prognosis value of OGD in COVID-19. These symptoms were recorded on admission from a cohort study of 5868 patients with confirmed or highly suspected COVID-19 infection included in the multicenter international HOPE Registry (NCT04334291). There was statistical relation in multivariate analysis for OGD in gender, more frequent in female 12.41% vs 8.67% in male, related to age, more frequent under 65 years, presence of hypertension, dyslipidemia, diabetes, smoke, renal insufficiency, lung, heart, cancer and neurological disease. We did not find statistical differences in pregnant (p = 0.505), patient suffering cognitive (p = 0.484), liver (p = 0.1) or immune disease (p = 0.32). There was inverse relation (protective) between OGD and prone positioning (0.005) and death (
YR 2021
FD 2021-03-01
LK http://hdl.handle.net/10668/17256
UL http://hdl.handle.net/10668/17256
LA en
DS RISalud
RD Apr 11, 2025