TY - JOUR AU - Moncayo-Donoso, Miguelangel AU - Rico-Llanos, Gustavo A. AU - Garzón-Alvarado, Diego A. AU - Becerra, José AU - Visser, Rick AU - Fontanilla, Marta R. PY - 2021 DO - 10.3390/polym13183187 UR - http://hdl.handle.net/10668/3462 T2 - Polymers AB - Although many bone substitutes have been designed and produced, the development of bone tissue engineering products that mimic the microstructural characteristics of native bone remains challenging. It has been shown that pore orientation within... LA - en PB - MDPI AG KW - BMP-2 KW - VEGF KW - Bone tissue engineering KW - Osteogenesis KW - Pore directionality KW - Type I collagen KW - Proteína morfogenética ósea 2 KW - Osteogénesis KW - Colágeno Tipo I KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Culture Techniques::Cell Engineering::Tissue Engineering KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Morphogenesis::Embryonic and Fetal Development::Organogenesis::Musculoskeletal Development::Bone Development::Osteogenesis KW - Medical Subject Headings::Chemicals and Drugs::Biomedical and Dental Materials::Biocompatible Materials::Bone Substitutes KW - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::Porosity KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Angiogenic Proteins::Vascular Endothelial Growth Factors::Vascular Endothelial Growth Factor A KW - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::Tensile Strength KW - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Polymers::Biopolymers::Collagen::Fibrillar Collagens::Collagen Type I TI - The Effect of Pore Directionality of Collagen Scaffolds on Cell Differentiation and In Vivo Osteogenesis TY - research article ER -