RT Journal Article T1 Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases. A1 Aheget, Houssam A1 Mazini, Loubna A1 Martin, Francisco A1 Belqat, Boutaïna A1 Marchal, Juan Antonio A1 Benabdellah, Karim K1 cancer pathogenesis K1 diagnostics K1 exosomes K1 molecular composition K1 therapeutics AB Exosomes are lipid bilayer particles released from cells into their surrounding environment. These vesicles are mediators of near and long-distance intercellular communication and affect various aspects of cell biology. In addition to their biological function, they play an increasingly important role both in diagnosis and as therapeutic agents. In this paper, we review recent literature related to the molecular composition of exosomes, paying special attention to their role in pathogenesis, along with their application as biomarkers and as therapeutic tools. In this context, we analyze the potential use of exosomes in biomedicine, as well as the limitations that preclude their wider application. SN 2072-6694 YR 2020 FD 2020-12-30 LK https://hdl.handle.net/10668/28418 UL https://hdl.handle.net/10668/28418 LA en DS RISalud RD Aug 16, 2025