TY - JOUR AU - Contreras-Montoya, Rafael AU - Arredondo-Amador, María AU - Escolano-Casado, Guillermo AU - Mañas-Torres, Mari C AU - Gonzalez, Mercedes AU - Conejero-Muriel, Mayte AU - Bhatia, Vaibhav AU - Diaz-Mochon, Juan J AU - Martinez-Augustin, Olga AU - de Medina, Fermin Sanchez AU - Lopez-Lopez, Modesto T AU - Conejero-Lara, Francisco AU - Gavira, Jose A AU - de Cienfuegos, Luis Alvarez PY - 2021 DO - 10.1021/acsami.1c00639 UR - http://hdl.handle.net/10668/17271 T2 - ACS applied materials & interfaces AB - Protein therapeutics have a major role in medicine in that they are used to treat diverse pathologies. Their three-dimensional structures not only offer higher specificity and lower toxicity than small organic compounds but also make them less stable,... LA - en PB - American Chemical Society KW - composite materials KW - drug delivery KW - insulin composite crystals KW - protein crystallization KW - protein therapeutics KW - supramolecular hydrogels KW - Animals KW - Crystallization KW - Drug Liberation KW - Humans KW - Hydrogels KW - Hypoglycemic Agents KW - Insulin KW - Male KW - Peptides KW - Protein Stability KW - Rats, Wistar TI - Insulin Crystals Grown in Short-Peptide Supramolecular Hydrogels Show Enhanced Thermal Stability and Slower Release Profile. TY - research article VL - 13 ER -