TY - JOUR AU - Ayala, Rosa AU - Rapado, Inmaculada AU - Onecha, Esther AU - Martinez-Cuadron, David AU - CarreƱo-Tarragona, Gonzalo AU - Bergua, Juan Miguel AU - Vives, Susana AU - Algarra, Jesus Lorenzo AU - Tormo, Mar AU - Martinez, Pilar AU - Serrano, Josefina AU - Herrera, Pilar AU - Ramos, Fernando AU - Salamero, Olga AU - Lavilla, Esperanza AU - Gil, Cristina AU - Lopez-Lorenzo, Jose Luis AU - Vidriales, Maria Belen AU - Labrador, Jorge AU - Falantes, Jose Francisco AU - Sayas, Maria Jose AU - Paiva, Bruno AU - Barragan, Eva AU - Prosper, Felipe AU - Sanz, Miguel Angel AU - Martinez-Lopez, Joaquin AU - Montesinos, Pau PY - 2021 DO - 10.3390/cancers13102458 SN - 2072-6694 UR - http://hdl.handle.net/10668/17913 T2 - Cancers AB - We sought to predict treatment responses and outcomes in older patients with newly diagnosed acute myeloid leukemia (AML) from our FLUGAZA phase III clinical trial (PETHEMA group) based on mutational status, comparing azacytidine (AZA) with... LA - en PB - MDPI AG KW - NGS KW - acute KW - azacytidine KW - clinical trials and observations KW - complete remission KW - cytarabine KW - genetic risk KW - leukemia KW - leukemic cells KW - myelocytic KW - myeloid neoplasia KW - older adults KW - prognostic factors KW - variants KW - Prognosis KW - Tumor Burden KW - fludarabine KW - Odds Ratio KW - Survival Analysis KW - Biomarkers KW - Cytogenetic Analysis KW - Genomics KW - High-Throughput Nucleotide Sequencing KW - Gene Frequency TI - The Mutational Landscape of Acute Myeloid Leukaemia Predicts Responses and Outcomes in Elderly Patients from the PETHEMA-FLUGAZA Phase 3 Clinical Trial. TY - research article VL - 13 ER -