TY - JOUR AU - Andreu-Bernabeu, Álvaro AU - Díaz-Caneja, Covadonga M AU - Costas, Javier AU - De Hoyos, Lucía AU - Stella, Carol AU - Gurriarán, Xaquín AU - Alloza, Clara AU - Fañanás, Lourdes AU - Bobes, Julio AU - González-Pinto, Ana AU - Crespo-Facorro, Benedicto AU - Martorell, Lourdes AU - Vilella, Elisabet AU - Muntané, Gerard AU - Nacher, Juan AU - Molto, María Dolores AU - Aguilar, Eduardo Jesús AU - Parellada, Mara AU - Arango, Celso AU - González-Peñas, Javier PY - 2022 DO - 10.1038/s41467-021-27598-6 UR - http://hdl.handle.net/10668/19535 T2 - Nature communications AB - Previous research suggests an association of loneliness and social isolation (LNL-ISO) with schizophrenia. Here, we demonstrate a LNL-ISO polygenic score contribution to schizophrenia risk in an independent case-control sample (N = 3,488). We then... LA - en KW - Alcoholism KW - Anxiety Disorders KW - Attention Deficit Disorder with Hyperactivity KW - Case-Control Studies KW - Female KW - Genetic Predisposition to Disease KW - Genome-Wide Association Study KW - Humans KW - Loneliness KW - Male KW - Mendelian Randomization Analysis KW - Multifactorial Inheritance KW - Phenotype KW - Schizophrenia KW - Social Isolation TI - Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia. TY - research article VL - 13 ER -