RT Journal Article T1 Fruit and Vegetable Consumption is Inversely Associated with Plasma Saturated Fatty Acids at Baseline in Predimed Plus Trial. A1 Dominguez-Lopez, Ines A1 Marhuenda-Muñoz, Maria A1 Tresserra-Rimbau, Anna A1 Hernaez, Alvaro A1 Moreno, Juan Jose A1 Martinez-Gonzalez, Miguel Angel A1 Salas-Salvado, Jordi A1 Corella, Dolores A1 Fito, Montserrat A1 Martinez, Jose Alfredo A1 Alonso-Gomez, Angel M A1 Wärnberg, Julia A1 Vioque, Jesus A1 Romaguera, Dora A1 Lopez-Miranda, Jose A1 Bernal-Lopez, M Rosa A1 Lapetra, Jose A1 Serra-Majem, J Luis A1 Bueno-Cavanillas, Aurora A1 Tur, Josep A A1 Martin-Sanchez, Vicente A1 Pinto, Xavier A1 Delgado-Rodriguez, Miguel A1 Matia-Martin, Pilar A1 Vidal, Josep A1 Vazquez, Clotilde A1 Daimiel, Lidia A1 Serra-Mir, Merce A1 Vazquez-Ruiz, Zenaida A1 Nishi, Stephanie K A1 Sorli, Jose V A1 Castañer, Olga A1 Abete, Itziar A1 Luna, Jessica Vaquero A1 Carabaño-Moral, Rosa A1 Asencio, Alberto A1 Prohens, Lara A1 Garcia-Rios, Antonio A1 Casas, Rosa A1 Gomez-Perez, Ana Maria A1 Santos-Lozano, Jose Manuel A1 Razquin, Cristina A1 Martinez, Maria Angeles A1 Saiz, Carmen A1 Robledo-Pastor, Vanesa A1 Zulet, Maria Angeles A1 Salaverria, Itziar A1 Eguaras, Sonia A1 Babio, Nancy A1 Malcampo, Mireia A1 Ros, Emilio A1 Estruch, Ramon A1 Lopez-Sabater, M Carmen A1 Lamuela-Raventos, Rosa M K1 MUFA K1 PREDIMED-Plus K1 PUFA K1 Dietary fats, Mediterranean diet AB Plasma fatty acids (FAs) are associated with the development of cardiovascular diseases and metabolic syndrome. The aim of our study is to assess the relationship between fruit and vegetable (F&V) consumption and plasma FAs and their subtypes. Plasma FAs are assessed in a cross-sectional analysis of a subsample of 240 subjects from the PREDIMED-Plus study. Participants are categorized into four groups of fruit, vegetable, and fat intake according to the food frequency questionnaire. Plasma FA analysis is performed using gas chromatography. Associations between FAs and F&V consumption are adjusted for age, sex, physical activity, body mass index (BMI), total energy intake, and alcohol consumption. Plasma saturated FAs are lower in groups with high F&V consumption (-1.20 mg cL-1 [95% CI: [-2.22, -0.18], p-value = 0.021), especially when fat intake is high (-1.74 mg cL-1 [95% CI: [-3.41, -0.06], p-value = 0.042). Total FAs and n-6 polyunsaturated FAs tend to be lower in high consumers of F&V only in the high-fat intake groups. F&V consumption is associated with lower plasma saturated FAs when fat intake is high. These findings suggest that F&V consumption may have different associations with plasma FAs depending on their subtype and on the extent of fat intake. PB Wiley YR 2021 FD 2021-07-28 LK http://hdl.handle.net/10668/18209 UL http://hdl.handle.net/10668/18209 LA en NO Domínguez-López I, Marhuenda-Muñoz M, Tresserra-Rimbau A, Hernáez Á, Moreno JJ, Martínez-González MÁ, et al. Fruit and Vegetable Consumption is Inversely Associated with Plasma Saturated Fatty Acids at Baseline in Predimed Plus Trial. Mol Nutr Food Res. 2021 Sep;65(17):e2100363 NO I.D.-L. is supported by the [FI_B 00256] from the FI-AGAUR Research Fel lowship Program, Generalitat de Catalunya and M.M.-M is supported bythe FPU17/00513 grant. Á.-H. is supported by the [CD17/00122] grant andS.K.N. is supported by a Canadian Institutes of Health Research (CIHR)Fellowship. We also thank all the volunteers for their participation in andthe personnel for their contribution to the PREDIMED-Plus trial. This re search was funded by CiCYT [AGL2016-75329-R] and CIBEROBN fromthe Instituto de Salud Carlos III, ISCIII from the Ministerio de Ciencia,Innovación y Universidades, (AEI/FEDER, UE), Generalitat de Catalunya(GC) [2017SGR196]. The PREDIMED-Plus trial was supported by the offi cial Spanish Institutions for funding scientific biomedical research, CIBERFisiopatología de la Obesidad y Nutrición (CIBERobn) and Instituto deSalud Carlos III (ISCIII), through the Fondo de Investigación para la Salud(FIS), which is co-funded by the European Regional Development Fund(four coordinated Fondo de Investigaciones Sanitarias projects lead byJ.S.-S. and J.V., including the following projects: PI13/00673, PI13/00492,PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618,PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873,PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347,PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926 and PI19/00781), the Especial ActionProject entitled Implementación y evaluación de una intervención inten siva sobre la actividad física Cohorte PREDIMED-Plus grant to J.S.-S., Eu ropean Research Council (Advanced Research Grant 2014–2019, 340918)to M.Á.M.-G., the Recercaixa grant to J.S.-S. (2013ACUP00194), grantsfrom the Consejería de Salud de la Junta de Andalucía (PI0458/2013,PS0358/2016, and PI0137/2018), a grant from the Generalitat Valenciana(PROMETEO/2017/017), a SEMERGEN grant, Fundació la Marató deTV3 (PI044003), 2017 SGR 1717 from Generalitat de Catalunya, a CICYTgrant provided by the Ministerio de Ciencia, Innovación y Universidades(AGL2016-75329-R), and funds from the European Regional Develop ment Fund (CB06/03 and CB12/03). DS RISalud RD Apr 4, 2025