RT Journal Article
T1 High-resolution anoscopy in HIV-infected men: Assessment of the learning curve and factors that improve the performance.
A1 Neukam, Karin
A1 Milanés Guisado, Yusnelkis
A1 Fontillón, María
A1 Merino, Laura
A1 Sotomayor, César
A1 Espinosa, Nuria
A1 López-Cortés, Luis F
A1 Viciana, Pompeyo
A1 SeVIHanal Study Group, 
K1 Anal squamous cell carcinoma
K1 High-resolution anoscopy
K1 Human papillomavirus
K1 Learning curve
K1 Liquid-based cytology
K1 Operator experience
AB To determine the required learning time for high-resolution anoscopy (HRA)-guided biopsy to detect histological high-risk squamous intraepithelial lesions (hHSIL) and to identify factors that impact on the training process. All HIV-infected, screening-naïve men-who-have-sex-with-men who underwent HRA conducted by one single observer from 2010 to 2017 in a Spanish HIV-outpatient clinic were analysed. Eighty-five (14.7%) of the 581 patients included presented hHSIL. The factors associated with the capacity to detect hHSIL [adjusted odds ratio (aOR), 95% confidence interval (95%CI)] were the presence of cytological HSIL (3.04, 1.78-5.21; p  The data support the growing evidence that the proposed training volume of 50-200 performances is underestimated. Extensive training of both anoscopist and pathologist is warranted and the development of tools to support the diagnostic performance may be considered.
YR 2019
FD 2019-02-01
LK http://hdl.handle.net/10668/13507
UL http://hdl.handle.net/10668/13507
LA en
DS RISalud
RD Apr 11, 2025