%0 Journal Article
%A Neukam, Karin
%A Milanés Guisado, Yusnelkis
%A Fontillón, María
%A Merino, Laura
%A Sotomayor, César
%A Espinosa, Nuria
%A López-Cortés, Luis F
%A Viciana, Pompeyo
%A SeVIHanal Study Group
%T High-resolution anoscopy in HIV-infected men: Assessment of the learning curve and factors that improve the performance.
%D 2019
%U http://hdl.handle.net/10668/13507
%X To determine the required learning time for high-resolution anoscopy (HRA)-guided biopsy to detect histological high-risk squamous intraepithelial lesions (hHSIL) and to identify factors that impact on the training process. All HIV-infected, screening-naïve men-who-have-sex-with-men who underwent HRA conducted by one single observer from 2010 to 2017 in a Spanish HIV-outpatient clinic were analysed. Eighty-five (14.7%) of the 581 patients included presented hHSIL. The factors associated with the capacity to detect hHSIL [adjusted odds ratio (aOR), 95% confidence interval (95%CI)] were the presence of cytological HSIL (3.04, 1.78-5.21; p  The data support the growing evidence that the proposed training volume of 50-200 performances is underestimated. Extensive training of both anoscopist and pathologist is warranted and the development of tools to support the diagnostic performance may be considered.
%K Anal squamous cell carcinoma
%K High-resolution anoscopy
%K Human papillomavirus
%K Learning curve
%K Liquid-based cytology
%K Operator experience
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