%0 Journal Article
%A Lopez-Perez, David
%A Redruello-Romero, Anaïs
%A Garcia-Rubio, Jesus
%A Arana, Carlos
%A Garcia-Escudero, Luis A
%A Tamayo, Francisco
%A Salmeron, Javier
%A Galvez, Julio
%A Leon, Josefa
%A Carazo, Angel
%T In Obese Patients With Type 2 Diabetes, Mast Cells in Omental Adipose Tissue Decrease the Surface Expression of CD45, CD117, CD203c, and FcϵRI.
%D 2022
%@ 1664-2392
%U http://hdl.handle.net/10668/20558
%X The paradigm of mast cells in type 2 diabetes is changing. Although they were first considered deleterious inflammatory cells, now they seem to be important players driving adipose tissue homeostasis. Here we have employed a flow cytometry-based approach for measuring the surface expression of 4 proteins (CD45, CD117, CD203c, and FcϵRI) on mast cells of omental (o-WAT) and subcutaneous white adipose tissue (s-WAT) in a cohort of 96 patients with morbid obesity. The cohort was split into three groups: non-T2D, pre-T2D, and T2D. Noteworthy, patients with T2D have a mild condition (HbA1c
%K adipose tissue
%K bariatric surgery
%K flow cytometry
%K mast cell
%K obesity
%K type 2 diabetes
%~