%0 Journal Article
%A Margarit, Cesar
%A López, Rafael
%A Anton, Antonio
%A Escobar, Yolanda
%A Casas, Ana
%A Cruz, Juan Jesús
%A Galvez, Rafael
%A Mañas, Ana
%A Zaragozá, Francisco
%T Breakthrough cancer pain - still a challenge.
%D 2012
%U http://hdl.handle.net/10668/1420
%X Breakthrough cancer pain is defined as transient pain exacerbation in patients with stable and controlled basal pain. Although variable, the prevalence of breakthrough cancer pain is high (33%-95%). According to the American Pain Foundation, breakthrough pain is observed in 50%-90% of all hospitalized cancer patients, in 89% of all patients admitted to homes for the elderly and terminal-patient care centers, and in 35% of all ambulatory care cancer patients. The management of breakthrough cancer pain should involve an interdisciplinary and multimodal approach. The introduction of new fentanyl formulations has represented a great advance and has notably improved treatment. Among these, the pectin-based intranasal formulation adjusts very well to the profile of breakthrough pain attacks, is effective, has a good toxicity profile, and allows for convenient dosing - affording rapid and effective analgesia with the added advantage of being easily administered by caregivers when patients are unable to collaborate.
%K Prevalence
%K Management
%K Diagnosis
%K Opioids
%K Prevalencia
%K Diagnóstico
%K Analgésicos Opioides
%K Fentanilo
%K Pectinas
%K Dolor intercurrente
%~