TY  - JOUR
AU  - Hurtado-Guerrero, Isaac
AU  - Pinto-Medel, Maria Jesús
AU  - Urbaneja, Patricia
AU  - Rodriguez-Bada, Jose Luis
AU  - León, Antonio
AU  - Guerrero, Miguel
AU  - Fernández, Óscar
AU  - Leyva, Laura
AU  - Oliver-Martos, Begoña
PY  - 2017
DO  - 10.1371/journal.pone.0170031
UR  - http://hdl.handle.net/10668/2680
T2  - PloS One
AB  - Interferon beta (IFNß) is a common treatment used for multiple sclerosis (MS) which acts through the activation of the JAK-STAT pathway. However, this therapy is not always effective and currently there are no reliable biomarkers to predict...
LA  - en
PB  - Public Libray of Science
KW  - Biomarcadores
KW  - Citometría de flujo
KW  - Humanos
KW  - Leucocitos mononucleares
KW  - Monocitos
KW  - Esclerosis múltiple
KW  - Fenotipo
KW  - Factor de Transcripción STAT1
KW  - Factor de Transcripción STAT2
KW  - Resultado del tratamiento
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biomarkers
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cell Separation::Flow Cytometry
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Interferons::Interferon Type I::Interferon-beta::Interferon beta-1a
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Interferons::Interferon Type I::Interferon-beta
KW  - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear
KW  - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Monocytes
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Adaptor Proteins, Signal Transducing::STAT Transcription Factors::STAT1 Transcription Factor
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Adaptor Proteins, Signal Transducing::STAT Transcription Factors::STAT2 Transcription Factor
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
TI  - Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß
TY  - research article
ER  -