RT Journal Article
T1 Incorporating the Gut Microbiome in the Risk Assessment of Xenobiotics and Identifying Beneficial Components for One Health.
A1 Ampatzoglou, Antonis
A1 Gruszecka-Kosowska, Agnieszka
A1 Torres-Sanchez, Alfonso
A1 Lopez-Moreno, Ana
A1 Cerk, Klara
A1 Ortiz, Pilar
A1 Monteoliva-Sanchez, Mercedes
A1 Aguilera, Margarita
K1 antimicrobial resistance
K1 gut microbiome
K1 microbiota disrupting chemicals
K1 next-generation probiotics
K1 next-generation risk assessment
K1 one health
K1 xenobiotics
AB Three areas of relevance to the gut microbiome in the context of One Health were explored; the incorporation of the microbiome in food safety risk assessment of xenobiotics; the identification and application of beneficial microbial components to various areas under One Health, and; specifically, in the context of antimicrobial resistance. Although challenging, focusing on the microbiota resilience, function and active components is critical for advancing the incorporation of microbiome data in the risk assessment of xenobiotics. Moreover, the human microbiota may be a promising source of beneficial components, with the potential to metabolize xenobiotics. These may have possible applications in several areas, e.g., in animals or plants for detoxification or in the environment for biodegradation. This approach would be of particular interest for antimicrobials, with the potential to ameliorate antimicrobial resistance development. Finally, the concept of resistance to xenobiotics in the context of the gut microbiome may deserve further investigation.
PB Frontiers Research Foundation
SN 1664-302X
YR 2022
FD 2022-03-031
LK http://hdl.handle.net/10668/20623
UL http://hdl.handle.net/10668/20623
LA en
NO Ampatzoglou A, Gruszecka-Kosowska A, Torres-Sánchez A, López-Moreno A, Cerk K, Ortiz P, et al.  Incorporating the Gut Microbiome in the Risk Assessment of Xenobiotics and Identifying Beneficial Components for One Health. Front Microbiol. 2022 May 4;13:872583.
DS RISalud
RD Apr 19, 2025