TY - JOUR AU - Castilla-Ortega, Estela AU - Blanco, Eduardo AU - Serrano, Antonia AU - Ladrón de Guevara-Miranda, David AU - Pedraz, María AU - Estivill-Torrús, Guillermo AU - Pavón, Francisco Javier AU - Rodríguez de Fonseca, Fernando AU - Santín, Luis J PY - 2015 DO - 10.1111/adb.12248 UR - http://hdl.handle.net/10668/9761 T2 - Addiction biology AB - We investigated the role of adult hippocampal neurogenesis in cocaine-induced conditioned place preference (CPP) behaviour and the functional brain circuitry involved. Adult hippocampal neurogenesis was pharmacologically reduced with temozolomide... LA - en KW - Brain networks connectivity KW - drug addiction vulnerability KW - early immediate gene c-Fos KW - extinction and reinstatement KW - principal components factorial analysis PCA KW - temozolomide TMZ KW - Animals KW - Antineoplastic Agents, Alkylating KW - Behavior, Animal KW - Brain KW - Choice Behavior KW - Cocaine KW - Conditioning, Psychological KW - Dacarbazine KW - Dentate Gyrus KW - Dopamine Uptake Inhibitors KW - Extinction, Psychological KW - Hippocampus KW - Male KW - Mice KW - Multivariate Analysis KW - Neural Pathways KW - Neurogenesis KW - Nucleus Accumbens KW - Paraventricular Hypothalamic Nucleus KW - Prefrontal Cortex KW - Proto-Oncogene Proteins c-fos KW - Temozolomide TI - Pharmacological reduction of adult hippocampal neurogenesis modifies functional brain circuits in mice exposed to a cocaine conditioned place preference paradigm. TY - research article VL - 21 ER -