RT Journal Article
T1 Virological outcome among HIV infected patients transferred from pediatric care to adult units in Madrid, Spain (1997-2017).
A1 Beltrán-Pavez, Carolina
A1 Gutiérrez-López, Miguel
A1 Rubio-Garrido, Marina
A1 Valadés-Alcaraz, Ana
A1 Prieto, Luis
A1 Ramos, José Tomás
A1 Jiménez De Ory, Santiago
A1 Navarro, Marisa
A1 Díez-Romero, Cristina
A1 Pulido, Federico
A1 Valencia, Eulalia
A1 Holguín, África
A1 Madrid Cohort of HIV-Infected Children integrated in the Pediatric Branch of the Spanish National AIDS Network (CoRISpe), 
AB The aim of this transversal study was to describe the virological and immunological features of HIV-infected youths transferred from pediatric to adult care units since 1997 vs. the non-transferred patients from the Madrid Cohort of HIV-infected children and adolescents in Spain. We included 106 non-transferred and 184 transferred patients under clinical follow-up in 17 public hospitals in Madrid by the end of December 2017. Virological and immunological outcomes were compared in transferred vs. non-transferred patients. ART drug resistance mutations and HIV-variants were analyzed in all subjects with available resistance pol genotypes and/or genotypic resistance profiles. Among the study cohort, 133 (72.3%) of 184 transferred and 75 (70.7%) of 106 non-transferred patients had available resistance genotypes. Most (88.9%) of transferred had ART experience at sampling. A third (33.3%) had had a triple-class experience. Acquired drug resistance (ADR) prevalence was significantly higher in pretreated transferred than non-transferred patients (71.8% vs. 44%; p = 0.0009), mainly to NRTI (72.8% vs. 31.1%; p 
YR 2020
FD 2020-10-09
LK https://hdl.handle.net/10668/24862
UL https://hdl.handle.net/10668/24862
LA en
DS RISalud
RD Apr 11, 2025