%0 Journal Article
%A Beltrán-Pavez, Carolina
%A Gutiérrez-López, Miguel
%A Rubio-Garrido, Marina
%A Valadés-Alcaraz, Ana
%A Prieto, Luis
%A Ramos, José Tomás
%A Jiménez De Ory, Santiago
%A Navarro, Marisa
%A Díez-Romero, Cristina
%A Pulido, Federico
%A Valencia, Eulalia
%A Holguín, África
%A Madrid Cohort of HIV-Infected Children integrated in the Pediatric Branch of the Spanish National AIDS Network (CoRISpe)
%T Virological outcome among HIV infected patients transferred from pediatric care to adult units in Madrid, Spain (1997-2017).
%D 2020
%U https://hdl.handle.net/10668/24862
%X The aim of this transversal study was to describe the virological and immunological features of HIV-infected youths transferred from pediatric to adult care units since 1997 vs. the non-transferred patients from the Madrid Cohort of HIV-infected children and adolescents in Spain. We included 106 non-transferred and 184 transferred patients under clinical follow-up in 17 public hospitals in Madrid by the end of December 2017. Virological and immunological outcomes were compared in transferred vs. non-transferred patients. ART drug resistance mutations and HIV-variants were analyzed in all subjects with available resistance pol genotypes and/or genotypic resistance profiles. Among the study cohort, 133 (72.3%) of 184 transferred and 75 (70.7%) of 106 non-transferred patients had available resistance genotypes. Most (88.9%) of transferred had ART experience at sampling. A third (33.3%) had had a triple-class experience. Acquired drug resistance (ADR) prevalence was significantly higher in pretreated transferred than non-transferred patients (71.8% vs. 44%; p = 0.0009), mainly to NRTI (72.8% vs. 31.1%; p 
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