TY - JOUR AU - Douillard, J-Y AU - Ostoros, G AU - Cobo, M AU - Ciuleanu, T AU - McCormack, R AU - Webster, A AU - Milenkova, T PY - 2014 DO - 10.1038/bjc.2013.721 SN - 0007-0920 UR - http://hdl.handle.net/10668/1847 T2 - British journal of cancer AB - BACKGROUND:Phase-IV, open-label, single-arm study (NCT01203917) to assess efficacy and safety/tolerability of first-line gefitinib in Caucasian patients with stage IIIA/B/IV, epidermal growth factor receptor (EGFR) mutation-positive non-small-cell... LA - en PB - Nature Publishing Group KW - Gefinitib KW - NSCLC KW - EGFR mutation KW - Caucasian KW - Neoplasias pulmonares KW - Estudios prospectivos KW - Inhibidores de proteína cinasas KW - Receptor del factor de crecimiento epidérmico KW - Antineoplásicos KW - Grupo de ascendencia continental europea KW - Progresión de la enfermedad KW - Supervivencia sin Enfermedad KW - Carcinoma de pulmón de células no pequeñas KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms::Bronchial Neoplasms::Carcinoma, Bronchogenic::Carcinoma, Non-Small-Cell Lung KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Survival Analysis::Disease-Free Survival KW - Medical Subject Headings::Named Groups::Persons::Population Groups::Continental Population Groups::European Continental Ancestry Group KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Neoplasm::Oncogenes::Proto-Oncogenes::Genes, erbB::Genes, erbB-1 KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal... KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Protein Kinase Inhibitors KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Quinazolines KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Tyrosine Kinases::Receptor Protein-Tyrosine Kinases::Receptor,... KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Young Adult KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adolescent TI - First-line gefitinib in Caucasian EGFR mutation-positive NSCLC patients: a phase-IV, open-label, single-arm study. TY - research article ER -