RT Journal Article
T1 Adopting a High-Polyphenolic Diet Is Associated with an Improved Glucose Profile: Prospective Analysis within the PREDIMED-Plus Trial.
A1 Tresserra-Rimbau, Anna
A1 Castro-Barquero, Sara
A1 Becerra-Tomas, Nerea
A1 Babio, Nancy
A1 Marinez-Gonzalez, Miguel Angel
A1 Corella, Dolores
A1 Fito, Montserrat
A1 Romaguera, Dora
A1 Vioque, Jesus
A1 Alonso-Gomez, Angel M
A1 Wärnberg, Julia
A1 Martinez, Jose Alfredo
A1 Serra-Majem, Luis
A1 Estruch, Ramon
A1 Tinahones, Francisco J
A1 Lapetra, Jose
A1 Pinto, Xavier
A1 Tur, Josep A
A1 Lopez-Miranda, Jose
A1 Cano-Ibañez, Naomi
A1 Delgado-Rodriguez, Miguel
A1 Matia-Martin, Pilar
A1 Daimiel, Lidia
A1 Martin Sanchez, Vicente
A1 Vidal, Josep
A1 Vazquez, Clotilde
A1 Ros, Emili
A1 Basterra, Francisco Javier
A1 Fernandez de la Puente, Maria
A1 Asensio, Eva M
A1 Castañer, Olga
A1 Bullon-Vela, Vanessa
A1 Tojal-Sierra, Lucas
A1 Gomez-Gracia, Enrique
A1 Cases-Perez, Eugenio
A1 Konieczna, Jadwiga
A1 Garcia-Rios, Antonio
A1 Casañas-Quintana, Tamara
A1 Bernal-Lopez, Maria Rosa
A1 Santos-Lozano, Jose Manuel
A1 Esteve-Luque, Virginia
A1 Bouzas, Cristina
A1 Vazquez-Ruiz, Zenaida
A1 Palau-Galindo, Antoni
A1 Barragan, Rocio
A1 Lopez Grau, Merce
A1 Razquin, Cristina
A1 Goicolea-Güemez, Leire
A1 Toledo, Estefania
A1 Vergaz, Manel Vila
A1 Lamuela-Raventos, Rosa M
A1 Salas-Salvado, Jordi
K1 HbA1c
K1 Mediterranean diet
K1 Antioxidants
K1 Flavonoids
AB Previous studies suggested that dietary polyphenols could reduce the incidence and complications of type-2 diabetes (T2D); although the evidence is still limited and inconsistent. This work analyzes whether changing to a diet with a higher polyphenolic content is associated with an improved glucose profile. At baseline, and at 1 year of follow-up visits, 5921 participants (mean age 65.0 ± 4.9, 48.2% women) who had overweight/obesity and metabolic syndrome filled out a validated 143-item semi-quantitative food frequency questionnaire (FFQ), from which polyphenol intakes were calculated. Energy-adjusted total polyphenols and subclasses were categorized in tertiles of changes. Linear mixed-effect models with random intercepts (the recruitment centers) were used to assess associations between changes in polyphenol subclasses intake and 1-year plasma glucose or glycosylated hemoglobin (HbA1c) levels. Increments in total polyphenol intake and some classes were inversely associated with better glucose levels and HbA1c after one year of follow-up. These associations were modified when the analyses were run considering diabetes status separately. To our knowledge, this is the first study to assess the relationship between changes in the intake of all polyphenolic groups and T2D-related parameters in a senior population with T2D or at high-risk of developing T2D.
PB MDPI
SN 2076-3921
YR 2022
FD 2022-02-01
LK http://hdl.handle.net/10668/20774
UL http://hdl.handle.net/10668/20774
LA en
NO Tresserra-Rimbau A, Castro-Barquero S, Becerra-Tomás N, Babio N, Martínez-González MÁ, Corella D, et al. Adopting a High-Polyphenolic Diet Is Associated with an Improved Glucose Profile: Prospective Analysis within the PREDIMED-Plus Trial. Antioxidants (Basel). 2022 Feb 4;11(2):316.
DS RISalud
RD Apr 6, 2025