TY  - JOUR
AU  - Lopez-Lozano, Jose-Maria
AU  - Lawes, Timothy
AU  - Nebot, Cesar
AU  - Beyaert, Arielle
AU  - Bertrand, Xavier
AU  - Hocquet, Didier
AU  - Aldeyab, Mamoon
AU  - Scott, Michael
AU  - Conlon-Bingham, Geraldine
AU  - Farren, David
AU  - Kardos, Gabor
AU  - Fesus, Adina
AU  - Rodriguez-Baño, Jesus
AU  - Retamar, Pilar
AU  - Gonzalo-Jimenez, Nieves
AU  - Gould, Ian M
PY  - 2019
DO  - 10.1038/s41564-019-0410-0
UR  - http://hdl.handle.net/10668/13800
T2  - Nature microbiology
AB  - Balancing access to antibiotics with the control of antibiotic resistance is a global public health priority. At present, antibiotic stewardship is informed by a 'use it and lose it' principle, in which antibiotic use by the population is linearly...
LA  - en
PB  - Nature Publishing Group
KW  - Risk factors
KW  - Epidemiology
KW  - Computational models
KW  - Antimicrobial resistance
KW  - Bacterial infection
KW  - Acinetobacter baumannii
KW  - Anti-Bacterial Agents
KW  - Antimicrobial Stewardship
KW  - Bacterial Infections
KW  - Bacterial Proteins
KW  - Drug Resistance, Bacterial
KW  - Escherichia coli
KW  - Europe
KW  - Humans
KW  - Incidence
KW  - Methicillin-Resistant Staphylococcus aureus
KW  - Models, Theoretical
KW  - Pseudomonas aeruginosa
KW  - Time Factors
TI  - A nonlinear time-series analysis approach to identify thresholds in associations between population antibiotic use and rates of resistance.
TY  - research article
VL  - 4
ER  -