RT Journal Article
T1 An international perspective on hospitalized patients with viral community-acquired pneumonia.
A1 Radovanovic, Dejan
A1 Sotgiu, Giovanni
A1 Jankovic, Mateja
A1 Mahesh, Padukudru Anand
A1 Marcos, Pedro Jorge
A1 Abdalla, Mohamed I
A1 Di Pasquale, Marta Francesca
A1 Gramegna, Andrea
A1 Terraneo, Silvia
A1 Blasi, Francesco
A1 Santus, Pierachille
A1 Aliberti, Stefano
A1 Reyes, Luis F
A1 Restrepo, Marcos I
A1 GLIMP Study Group, 
K1 Community acquired pneumonia
K1 Influenza
K1 Oseltamivir
K1 Testing
K1 Viral pneumonia
K1 Viral swab
AB Who should be tested for viruses in patients with community acquired pneumonia (CAP), prevalence and risk factors for viral CAP are still debated. We evaluated the frequency of viral testing, virus prevalence, risk factors and treatment coverage with oseltamivir in patients admitted for CAP. Secondary analysis of GLIMP, an international, multicenter, point-prevalence study of hospitalized adults with CAP. Testing frequency, prevalence of viral CAP and treatment with oseltamivir were assessed among patients who underwent a viral swab. Univariate and multivariate analysis was used to evaluate risk factors. 553 (14.9%) patients with CAP underwent nasal swab. Viral CAP was diagnosed in 157 (28.4%) patients. Influenza virus was isolated in 80.9% of cases. Testing frequency and viral CAP prevalence were inhomogeneous across the participating centers. Obesity (OR 1.59, 95%CI: 1.01-2.48; p = 0.043) and need for invasive mechanical ventilation (OR 1.62, 95%CI: 1.02-2.56; p = 0.040) were independently associated with viral CAP. Prevalence of empirical treatment with oseltamivir was 5.1%. In an international scenario, testing frequency for viruses in CAP is very low. The most common cause of viral CAP is Influenza virus. Obesity and need for invasive ventilation represent independent risk factors for viral CAP. Adherence to recommendations for treatment with oseltamivir is poor.
YR 2018
FD 2018-11-04
LK http://hdl.handle.net/10668/13156
UL http://hdl.handle.net/10668/13156
LA en
DS RISalud
RD Apr 9, 2025