TY - JOUR AU - Sanchez-Illana, Angel AU - Nuñez-Ramiro, Antonio AU - Cernada, María AU - Parra-Llorca, Anna AU - Valverde, Eva AU - Blanco, Dorotea AU - Moral-Pumarega, Maria Teresa AU - Cabañas, Fernando AU - Boix, Hector AU - Pavon, Antonio AU - Chaffanel, Mercedes AU - Benavente-Fernandez, Isabel AU - Tofe, Ines AU - Loureiro, Begoña AU - Fernandez-Lorenzo, José R AU - Fernandez-Colomer, Belen AU - Garcia-Robles, Ana AU - Kuligowski, Julia AU - Vento, Maximo AU - HYPOTOP Study Group PY - 2017 DO - 10.1038/s41598-017-17202-7 UR - http://hdl.handle.net/10668/11885 T2 - Scientific reports AB - Therapeutic hypothermia (TH) initiated within 6 h from birth is the most effective therapeutic approach for moderate to severe hypoxic-ischemic encephalopathy (HIE). However, underlying mechanisms and effects on the human metabolism are not yet fully... LA - en PB - Nature Publishing Group KW - Pyruvic Acid KW - Lactic Acid KW - Metabolism KW - Mass Spectrometry KW - Chromatography, Gas KW - 3-Hydroxybutyric Acid KW - Acetoacetates KW - Biomarkers KW - Case-Control Studies KW - Female KW - Gas Chromatography-Mass Spectrometry KW - Humans KW - Hypothermia, Induced KW - Hypoxia-Ischemia, Brain KW - Infant, Newborn KW - Ketone Bodies KW - Lactic Acid KW - Limit of Detection KW - Male KW - Pyruvic Acid TI - Evolution of Energy Related Metabolites in Plasma from Newborns with Hypoxic-Ischemic Encephalopathy during Hypothermia Treatment. TY - research article VL - 7 ER -