TY - JOUR AU - Fernandez-Serra, Antonio AU - Moura, David S. AU - Sanchez-Izquierdo, María Dolores AU - Calabuig-Fariñas, Silvia AU - Lopez-Alvarez, Maria AU - Martínez-Martínez, Andrea AU - Carrasco-Garcia, Irene AU - Ramírez-Calvo, Marta AU - Blanco-Alcaina, Elena AU - López-Reig, Raquel AU - Obrador-Hevia, Antonia AU - Alemany, Regina AU - Gutierrez, Antonio AU - Hindi, Nadia AU - Poveda, Andres AU - Lopez-Guerrero, Jose A. AU - Martin-Broto, Javier PY - 2020 DO - 10.3390/cancers12102979 UR - http://hdl.handle.net/10668/4579 T2 - Cancers AB - MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression at the post-transcriptional level, and they have been described as being associated with tumor prognosis. Here, miRNA profiling was planned to explore new molecular... LA - en PB - MDPI KW - GIST KW - let-7e KW - Prognostic biomarkers KW - Caspase-3 KW - miR-550 KW - Gastrointestinal stromal tumors KW - MicroRNA KW - Prognosis KW - Target genes KW - Tumores del estroma gastrointestinal KW - MicroARNs KW - Pronóstico KW - Biomarcadores KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Antisense Elements (Genetics)::RNA, Antisense::MicroRNAs KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Endopeptidases::Cysteine Endopeptidases::Caspases::Caspases, Effector::Caspase 3 KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Paraffin KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Connective and Soft Tissue::Neoplasms, Connective Tissue::Gastrointestinal Stromal Tumors KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers TI - Prognostic Impact of let-7e MicroRNA and Its Target Genes in Localized High-Risk Intestinal GIST: A Spanish Group for Research on Sarcoma (GEIS) Study TY - research article ER -