RT Journal Article
T1 Severity Scores in COVID-19 Pneumonia: a Multicenter, Retrospective, Cohort Study.
A1 Artero, Arturo
A1 Madrazo, Manuel
A1 Fernandez-Garces, Mar
A1 Muiño-Miguez, Antonio
A1 Gonzalez-Garcia, Andres
A1 Crestelo-Vieitez, Anxela
A1 Garcia-Guijarro, Elena
A1 Fonseca-Aizpuru, Eva Maria
A1 Garcia-Gomez, Miriam
A1 Areses-Manrique, Maria
A1 Martinez-Cilleros, Carmen
A1 Fidalgo-Moreno, Maria Del Pilar
A1 Loureiro Amigo, Jose
A1 Gil-Sanchez, Ricardo
A1 Rabadan-Pejenaute, Elisa
A1 Abella-Vazquez, Lucy
A1 Cañizares-Navarro, Ruth
A1 Solis-Marquinez, Marta Nataya
A1 Carrasco-Sanchez, Francisco Javier
A1 Gonzalez-Moraleja, Julio
A1 Montero-Rivas, Lorena
A1 Escobar-Sevilla, Joaquin
A1 Martin-Escalante, Maria Dolores
A1 Gómez-Huelgas, Ricardo
A1 Ramos-Rincon, Jose Manuel
K1 COVID-19
K1 CURB-65
K1 PSI
K1 Community-acquired pneumonia
K1 qSOFA
K1 Area de Gestión Sanitaria Sur de Córdoba
AB Identification of patients on admission to hospital with coronavirus infectious disease 2019 (COVID-19) pneumonia who can develop poor outcomes has not yet been comprehensively assessed. To compare severity scores used for community-acquired pneumonia to identify high-risk patients with COVID-19 pneumonia. PSI, CURB-65, qSOFA, and MuLBSTA, a new score for viral pneumonia, were calculated on admission to hospital to identify high-risk patients for in-hospital mortality, admission to an intensive care unit (ICU), or use of mechanical ventilation. Area under receiver operating characteristics curve (AUROC), sensitivity, and specificity for each score were determined and AUROC was compared among them. Patients with COVID-19 pneumonia included in the SEMI-COVID-19 Network. We examined 10,238 patients with COVID-19. Mean age of patients was 66.6 years and 57.9% were males. The most common comorbidities were as follows: hypertension (49.2%), diabetes (18.8%), and chronic obstructive pulmonary disease (12.8%). Acute respiratory distress syndrome (34.7%) and acute kidney injury (13.9%) were the most common complications. In-hospital mortality was 20.9%. PSI and CURB-65 showed the highest AUROC (0.835 and 0.825, respectively). qSOFA and MuLBSTA had a lower AUROC (0.728 and 0.715, respectively). qSOFA was the most specific score (specificity 95.7%) albeit its sensitivity was only 26.2%. PSI had the highest sensitivity (84.1%) and a specificity of 72.2%. PSI and CURB-65, specific severity scores for pneumonia, were better than qSOFA and MuLBSTA at predicting mortality in patients with COVID-19 pneumonia. Additionally, qSOFA, the simplest score to perform, was the most specific albeit the least sensitive.
PB Springer
YR 2021
FD 2021-02-11
LK http://hdl.handle.net/10668/17163
UL http://hdl.handle.net/10668/17163
LA en
NO Artero A, Madrazo M, Fernández-Garcés M, Muiño Miguez A, González García A, Crestelo Vieitez A, et al. Severity Scores in COVID-19 Pneumonia: a Multicenter, Retrospective, Cohort Study. J Gen Intern Med. 2021 May;36(5):1338-1345
DS RISalud
RD Jul 3, 2025