RT Journal Article
T1 Severity Scores in COVID-19 Pneumonia: a Multicenter, Retrospective, Cohort Study.
A1 Artero, Arturo
A1 Madrazo, Manuel
A1 Fernández-Garcés, Mar
A1 Muiño Miguez, Antonio
A1 González García, Andrés
A1 Crestelo Vieitez, Anxela
A1 García Guijarro, Elena
A1 Fonseca Aizpuru, Eva María
A1 García Gómez, Miriam
A1 Areses Manrique, María
A1 Martinez Cilleros, Carmen
A1 Fidalgo Moreno, María Del Pilar
A1 Loureiro Amigo, José
A1 Gil Sánchez, Ricardo
A1 Rabadán Pejenaute, Elisa
A1 Abella Vázquez, Lucy
A1 Cañizares Navarro, Ruth
A1 Solís Marquínez, Marta Nataya
A1 Carrasco Sánchez, Francisco Javier
A1 González Moraleja, Julio
A1 Montero Rivas, Lorena
A1 Escobar Sevilla, Joaquín
A1 Martín Escalante, María Dolores
A1 Gómez-Huelgas, Ricardo
A1 Ramos-Rincón, José Manuel
A1 SEMI-COVID-19 Network, 
K1 COVID-19
K1 CURB-65
K1 PSI
K1 community-acquired pneumonia
K1 qSOFA
AB Identification of patients on admission to hospital with coronavirus infectious disease 2019 (COVID-19) pneumonia who can develop poor outcomes has not yet been comprehensively assessed. To compare severity scores used for community-acquired pneumonia to identify high-risk patients with COVID-19 pneumonia. PSI, CURB-65, qSOFA, and MuLBSTA, a new score for viral pneumonia, were calculated on admission to hospital to identify high-risk patients for in-hospital mortality, admission to an intensive care unit (ICU), or use of mechanical ventilation. Area under receiver operating characteristics curve (AUROC), sensitivity, and specificity for each score were determined and AUROC was compared among them. Patients with COVID-19 pneumonia included in the SEMI-COVID-19 Network. We examined 10,238 patients with COVID-19. Mean age of patients was 66.6 years and 57.9% were males. The most common comorbidities were as follows: hypertension (49.2%), diabetes (18.8%), and chronic obstructive pulmonary disease (12.8%). Acute respiratory distress syndrome (34.7%) and acute kidney injury (13.9%) were the most common complications. In-hospital mortality was 20.9%. PSI and CURB-65 showed the highest AUROC (0.835 and 0.825, respectively). qSOFA and MuLBSTA had a lower AUROC (0.728 and 0.715, respectively). qSOFA was the most specific score (specificity 95.7%) albeit its sensitivity was only 26.2%. PSI had the highest sensitivity (84.1%) and a specificity of 72.2%. PSI and CURB-65, specific severity scores for pneumonia, were better than qSOFA and MuLBSTA at predicting mortality in patients with COVID-19 pneumonia. Additionally, qSOFA, the simplest score to perform, was the most specific albeit the least sensitive.
YR 2021
FD 2021-02-11
LK http://hdl.handle.net/10668/17163
UL http://hdl.handle.net/10668/17163
LA en
DS RISalud
RD Apr 19, 2025