TY - JOUR AU - Corella, Dolores AU - Asensio, Eva M AU - Coltell, Oscar AU - Sorlí, José V AU - Estruch, Ramón AU - Martínez-González, Miguel Ángel AU - Salas-Salvadó, Jordi AU - Castañer, Olga AU - Arós, Fernando AU - Lapetra, José AU - Serra-Majem, Lluís AU - Gómez-Gracia, Enrique AU - Ortega-Azorín, Carolina AU - Fiol, Miquel AU - Espino, Javier Díez AU - Díaz-López, Andrés AU - Fitó, Montserrat AU - Ros, Emilio AU - Ordovás, José M PY - 2016 DO - 10.1186/s12933-015-0327-8 UR - http://hdl.handle.net/10668/9710 T2 - Cardiovascular diabetology AB - Circadian rhythms regulate key biological processes influencing metabolic pathways. Disregulation is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). Circadian rhythms are generated by a transcriptional autoregulatory feedback... LA - en KW - Aged KW - Aged, 80 and over KW - CLOCK Proteins KW - Cardiovascular Diseases KW - Chi-Square Distribution KW - Circadian Rhythm KW - Diabetes Mellitus, Type 2 KW - Diet, Mediterranean KW - Gene Frequency KW - Gene-Environment Interaction KW - Genetic Predisposition to Disease KW - Heterozygote KW - Homozygote KW - Humans KW - Incidence KW - Kaplan-Meier Estimate KW - Longitudinal Studies KW - Male KW - Middle Aged KW - Multivariate Analysis KW - Phenotype KW - Polymorphism, Single Nucleotide KW - Proportional Hazards Models KW - Protective Factors KW - Risk Assessment KW - Risk Factors KW - Spain KW - Time Factors KW - Treatment Outcome TI - CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial. TY - research article VL - 15 ER -