RT Journal Article
T1 Consensus Statement on Hemostatic Management, Anticoagulation, and Antiplatelet Therapy in Liver Transplantation.
A1 Montalva, Eva
A1 Rodriguez-Peralvarez, Manuel
A1 Blasi, Annabel
A1 Bonanad, Santiago
A1 Gavín, Olga
A1 Hierro, Loreto
A1 Llado, Laura
A1 Llop, Elba
A1 Pozo-Laderas, Juan Carlos
A1 Colmenero, Jordi
K1 Liver transplantation
K1 Factor Xa inhibitors
K1 Platelet aggregation inhibitors
K1 Waiting lists
K1 Anesthesiologists
AB Anticoagulation and antiplatelet therapies are increasingly used in liver transplant (LT) candidates and recipients due to cardiovascular comorbidities, portal vein thrombosis, or to manage posttransplant complications. The implementation of the new direct-acting oral anticoagulants and the recently developed antiplatelet drugs is a great challenge for transplant teams worldwide, as their activity must be monitored and their complications managed, in the absence of robust scientific evidence. In this changing and clinically heterogeneous scenario, the Spanish Society of Liver Transplantation and the Spanish Society of Thrombosis and Haemostasis aimed to achieve consensus regarding the indications, drugs, dosing, and timing of anticoagulation and antiplatelet therapies initiated from the inclusion of the patient on the waiting list to post-LT surveillance. A multidisciplinary group of experts composed by transplant hepatologists, surgeons, hematologists, transplant-specialized anesthesiologists, and intensivists performed a comprehensive review of the literature and identified 21 clinically relevant questions using the patient-intervention-comparison-outcome format. A preliminary list of recommendations was drafted and further validated using a modified Delphi approach by a panel of 24 transplant delegates, each representing a LT institution in Spain. The present consensus statement contains the key recommendations together with the core supporting scientific evidence, which will provide guidance for improved and more homogeneous clinical decision making.
PB Lippincott Williams & Wilkins
YR 2021
FD 2021-09-18
LK http://hdl.handle.net/10668/19869
UL http://hdl.handle.net/10668/19869
LA en
NO Montalvá E, Rodríguez-Perálvarez M, Blasi A, Bonanad S, Gavín O, Hierro L, et al. Consensus Statement on Hemostatic Management, Anticoagulation, and Antiplatelet Therapy in Liver Transplantation. Transplantation. 2022 Jun 1;106(6):1123-1131
DS RISalud
RD Apr 10, 2025