TY - JOUR AU - Rittmeyer, Achim AU - Barlesi, Fabrice AU - Waterkamp, Daniel AU - Park, Keunchil AU - Ciardiello, Fortunato AU - von-Pawel, Joachim AU - Gadgeel, Shirish M AU - Hida, Toyoaki AU - Kowalski, Dariusz M AU - Dols, Manuel Cobo AU - Cortinovis, Diego L AU - Leach, Joseph AU - Polikoff, Jonathan AU - Barrios, Carlos AU - Kabbinavar, Fairooz AU - Frontera, Osvaldo Aren AU - De-Marinis, Filippo AU - Turna, Hande AU - Lee, Jong-Seok AU - Ballinger, Marcus AU - Kowanetz, Marcin AU - He, Pei AU - Chen, Daniel S AU - Sandler, Alan AU - Gandara, David R PY - 2017 DO - 10.1016/S0140-6736(16)32517-X UR - http://hdl.handle.net/10668/10684 T2 - Lancet (London, England) AB - Atezolizumab is a humanised antiprogrammed death-ligand 1 (PD-L1) monoclonal antibody that inhibits PD-L1 and programmed death-1 (PD-1) and PD-L1 and B7-1 interactions, reinvigorating anticancer immunity. We assessed its efficacy and safety versus... LA - en KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Agents KW - Carcinoma, Non-Small-Cell Lung KW - Disease-Free Survival KW - Adult KW - Aged KW - Aged, 80 and over KW - Antibodies, Monoclonal KW - Docetaxel KW - Drug Administration Schedule KW - Female KW - Humans KW - Infusions, Intravenous KW - Kaplan-Meier Estimate KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Taxoids KW - Treatment Outcome TI - Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial. TY - research article VL - 389 ER -