%0 Journal Article
%A Martin-Pelaez, Sandra
%A Serra-Majem, Lluis
%A Cano-Ibañez, Naomi
%A Martinez-Gonzalez, Miguel Angel
%A Salas-Salvado, Jordi
%A Corella, Dolores
%A Lassale, Camille
%A Martinez, Jose Alfredo
%A Alonso-Gomez, Angel M
%A Wärnberg, Julia
%A Vioque, Jesus
%A Romaguera, Dora
%A Lopez-Miranda, Jose
%A Estruch, Ramon
%A Tinahones, Francisco J
%A Lapetra, Jose
%A Fernandez-Aranda, Fernando
%A Bueno-Cavanillas, Aurora
%A Tur, Josep A
%A Martin, Vicente
%A Pinto, Xavier
%A Delgado-Rodriguez, Miguel
%A Matia, Pilar
%A Vidal, Josep
%A Vazquez, Clotilde
%A Daimiel, Lidia
%A Ros, Emili
%A Toledo, Estefania
%A Nishi, Stephanie K
%A Sorli, Jose V
%A Malcampo, Mireia
%A Zulet, M Angeles
%A Moreno-Rodriguez, Anai
%A Cueto-Galan, Raquel
%A Vivancos-Aparicio, Diego
%A Colom, Antoni
%A Garcia-Rios, Antonio
%A Casas, Rosa
%A Bernal-Lopez, M Rosa
%A Santos-Lozano, Jose Manuel
%A Vazquez, Zenaida
%A Gomez-Martinez, Carlos
%A Ortega-Azorin, Carolina
%A Del Val, Jose Luís
%A Abete, Itziar
%A Goikoetxea-Bahon, Amaia
%A Pascual, Elena
%A Becerra-Tomas, Nerea
%A Chillaron, Juan J
%A Sanchez-Villegas, Almudena
%T Contribution of cardio-vascular risk factors to depressive status in the PREDIMED-PLUS Trial. A cross-sectional and a 2-year longitudinal study.
%D 2022
%U http://hdl.handle.net/10668/20422
%X Cardio-vascular disease and depression are thought to be closely related, due to shared risk factors. The aim of the study was to determine the association between cardio-vascular risk (CVR) factors and depressive status in a population (55-75 years) with metabolic syndrome (MetS) from the PREDIMED-Plus trial. Participants were classified into three groups of CVR according to the Framingham-based REGICOR function: (1) low (LR), (2) medium (MR) or (3) high/very high (HR). The Beck Depression Inventory-II (BDI-II) was used to assess depressive symptoms at baseline and after 2 years. The association between CVR and depressive status at baseline (n = 6545), and their changes after 2 years (n = 4566) were evaluated through multivariable regression models (logistic and linear models). HR women showed higher odds of depressive status than LR [OR (95% CI) = 1.78 (1.26, 2.50)]. MR and HR participants with total cholesterol  Improving cardiovascular health could prevent the onset of depression in the elderly. Diabetes and total cholesterol in individuals at high CVR, may play a specific role in the precise response. 
%K Aged
%K Cholesterol
%K Cross-sectional studies
%K Depression
%K Diabetes mellitus
%~