RT Journal Article
T1 Agreement and repeatability of objective systems for assessment of the tear film.
A1 Fernández, Joaquín
A1 Rodríguez-Vallejo, Manuel
A1 Martínez, Javier
A1 Tauste, Ana
A1 García-Montesinos, Javier
A1 Piñero, David P
K1 Laser refractive surgery
K1 Non-invasive break-up time
K1 Objective systems
K1 Ocular scatter index
K1 Tear film stability
AB To assess the agreement and repeatability of two objective systems for measuring the tear film stability. Retrospective analysis of the tear film stability of 99 healthy right eyes measured with a videokeratoscope (VK) and the Optical Quality Analysis System (OQAS, Visiometrics). Two consecutive measures were taken with both systems, with an interval of 10 min between them. Variables included in the study were first and mean non-invasive break-up times (NIBUT and MNIBUT) measured with VK, and mean and standard deviation of the optical scattering index (OSIm and OSIsd) measured with OQAS. The agreement and repeatability of grading scales provided by both devices were also evaluated using the Cohen's k with quadratic weights. The Ocular Surface Disease index (OSDI) questionnaire was also passed out to all subjects. Correlations and associations between subjective and objective metrics were analyzed. Significant differences were found between consecutive measurements of NIBUT (p = 0.04) and MNIBUT (p = 0.01), but not for OSIm (p = 0.11) and OSIsd (p = 0.50). Grading scales resulted in fair (k = 0.20) or poor agreement (k = 0.04) between systems depending if the first or second trial was considered. The repeatability of the grading scale was good for OQAS (k = 0.59) and fair for VK (k = 0.37). No significant correlations or associations were found between OSDI and any of the metrics obtained with both devices (p ≥ 0.36). The two devices evaluated cannot be used interchangeably for the assessment of tear film stability. Good intrasession repeatability was obtained for tear film grading of the OQAS whereas it was fair for VK.
YR 2018
FD 2018-04-18
LK http://hdl.handle.net/10668/12368
UL http://hdl.handle.net/10668/12368
LA en
DS RISalud
RD Apr 12, 2025