RT Journal Article
T1 Analgesic effect of a single-dose of perineural dexamethasone on ultrasound-guided femoral nerve block after total knee replacement
A1 Morales-Munoz, C.
A1 Sanchez-Ramos, J. L.
A1 Diaz-Lara, M. D.
A1 Gonzalez-Gonzalez, J.
A1 Gallego-Alonso, I.
A1 Hernandez-del-Castillo, M. S.
K1 Dexamethasone
K1 Femoral nerve block
K1 Postoperative analgesia
K1 Total knee replacement
K1 Brachial-plexus blockade
K1 Peripheral-nerve
K1 Adjuvant dexamethasone
K1 Interscalene block
K1 Randomized-trials
K1 In-vitro
K1 Bupivacaine
K1 Duration
K1 Metaanalysis
K1 Ropivacaine
AB Introduction: Total knee replacement is usually a very painful procedure. A single-dose of femoral nerve block has been shown to provide similar analgesia to an epidural, with fewer side effects, but limited in time.Objective: To compare the analgesia provided by dexamethasone used at perineural level in the femoral nerve block after total knee replacement with the one used at intravenous level, and with that of a control group.Material and methods: A prospective, randomised, double-blind controlled trial was conducted on 81 patients randomly assigned to one of three groups: 1) IV dexamethasone (8 mg); 2) perineural dexamethasone (8 mg), and 3) placebo. All patients received 20ml of ropivacaine 0.5% for femoral nerve block. The primary outcome was the duration of the sensory-analgesic block of the femoral nerve block. The secondary outcomes included pain intensity measurements, patient satisfaction, and incidence of complications.Results: Randomisation was effective. Analgesia duration was significantly higher (P
PB Elsevier science bv
SN 0034-9356
YR 2017
FD 2017-01-01
LK http://hdl.handle.net/10668/18871
UL http://hdl.handle.net/10668/18871
LA es
DS RISalud
RD Apr 14, 2025