%0 Journal Article
%A Morales-Munoz, C.
%A Sanchez-Ramos, J. L.
%A Diaz-Lara, M. D.
%A Gonzalez-Gonzalez, J.
%A Gallego-Alonso, I.
%A Hernandez-del-Castillo, M. S.
%T Analgesic effect of a single-dose of perineural dexamethasone on ultrasound-guided femoral nerve block after total knee replacement
%D 2017
%@ 0034-9356
%U http://hdl.handle.net/10668/18871
%X Introduction: Total knee replacement is usually a very painful procedure. A single-dose of femoral nerve block has been shown to provide similar analgesia to an epidural, with fewer side effects, but limited in time.Objective: To compare the analgesia provided by dexamethasone used at perineural level in the femoral nerve block after total knee replacement with the one used at intravenous level, and with that of a control group.Material and methods: A prospective, randomised, double-blind controlled trial was conducted on 81 patients randomly assigned to one of three groups: 1) IV dexamethasone (8 mg); 2) perineural dexamethasone (8 mg), and 3) placebo. All patients received 20ml of ropivacaine 0.5% for femoral nerve block. The primary outcome was the duration of the sensory-analgesic block of the femoral nerve block. The secondary outcomes included pain intensity measurements, patient satisfaction, and incidence of complications.Results: Randomisation was effective. Analgesia duration was significantly higher (P
%K Dexamethasone
%K Femoral nerve block
%K Postoperative analgesia
%K Total knee replacement
%K Brachial-plexus blockade
%K Peripheral-nerve
%K Adjuvant dexamethasone
%K Interscalene block
%K Randomized-trials
%K In-vitro
%K Bupivacaine
%K Duration
%K Metaanalysis
%K Ropivacaine
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