TY - JOUR AU - Vida, Margarita AU - Rivera, Patricia AU - Gavito, Ana Luisa AU - Suárez, Juan AU - Pavón, Francisco Javier AU - Arrabal, Sergio AU - Romero-Cuevas, Miguel AU - Bautista, Dolores AU - Martínez, Ana AU - Rodríguez de Fonseca, Fernando AU - Serrano, Antonia AU - Baixeras, Elena PY - 2014 DO - 10.1371/journal.pone.0090016 UR - http://hdl.handle.net/10668/1976 T2 - PloS One AB - De novo lipogenesis and hypercaloric diets are thought to contribute to increased fat mass, particularly in abdominal fat depots. CB1 is highly expressed in adipose tissue, and CB1-mediated signalling is associated with stimulation of lipogenesis and... LA - en PB - Public Library of Science KW - Tejido adiposo blanco KW - Alimentación rica en grasa KW - Carbohidratos dietéticos KW - Riñón KW - Lipogénesis KW - Peso corporal KW - Obesidad KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Diet, High-Fat KW - Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Dietary Carbohydrates KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Pharmacological Processes::Down-Regulation KW - Medical Subject Headings::Anatomy::Urogenital System::Urinary Tract::Kidney KW - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipogenesis KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Piperidines KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Pyrazoles KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats::Rats, Wistar KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Cannabinoid::Receptor, Cannabinoid, CB1 KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction KW - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Time::Time Factors KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors KW - Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White TI - CB1 blockade potentiates down-regulation of lipogenic gene expression in perirenal adipose tissue in high carbohydrate diet-induced obesity. TY - research article ER -