RT Journal Article T1 Perivalvular Extension of Infective Endocarditis After Transcatheter Aortic Valve Replacement. A1 Panagides, Vassili A1 Del Val, David A1 Abdel-Wahab, Mohamed A1 Mangner, Norman A1 Durand, Eric A1 Ihlemann, Nikolaj A1 Urena, Marina A1 Pellegrini, Costanza A1 Giannini, Francesco A1 Gasior, Tomasz A1 Wojakowski, Wojtek A1 Landt, Martin A1 Auffret, Vincent A1 Sinning, Jan Malte A1 Cheema, Asim N A1 Nombela-Franco, Luis A1 Chamandi, Chekrallah A1 Campelo-Parada, Francisco A1 Munoz-Garcia, Erika A1 Herrmann, Howard C A1 Testa, Luca A1 Kim, Won Keun A1 Castillo, Juan Carlos A1 Alperi, Alberto A1 Tchetche, Didier A1 Bartorelli, Antonio L A1 Kapadia, Samir A1 Stortecky, Stefan A1 Amat-Santos, Ignacio A1 Wijeysundera, Harindra C A1 Lisko, John A1 Gutiérrez-Ibanes, Enrique A1 Serra, Vicenç A1 Salido, Luisa A1 Alkhodair, Abdullah A1 Livi, Ugolino A1 Chakravarty, Tarun A1 Lerakis, Stamatios A1 Vilalta, Victoria A1 Regueiro, Ander A1 Romaguera, Rafael A1 Kappert, Utz A1 Barbanti, Marco A1 Masson, Jean Bernard A1 Maes, Frédéric A1 Fiorina, Claudia A1 Miceli, Antonio A1 Kodali, Susheel A1 Ribeiro, Henrique B A1 Mangione, Jose Armando A1 Sandoli de Brito, Fabio A1 Actis Dato, Guglielmo Mario A1 Rosato, Francesco A1 Ferreira, Maria Cristina A1 Correia de Lima, Valter A1 Colafranceschi, Alexandre Siciliano A1 Abizaid, Alexandre A1 Marino, Marcos Antonio A1 Esteves, Vinicius A1 Andrea, Julio A1 Godinho, Roger R A1 Alfonso, Fernando A1 Eltchaninoff, Helene A1 Søndergaard, Lars A1 Himbert, Dominique A1 Husser, Oliver A1 Latib, Azeem A1 Le Breton, Hervé A1 Servoz, Clement A1 Pascual, Isaac A1 Siddiqui, Saif A1 Olivares, Paolo A1 Hernandez-Antolin, Rosana A1 Webb, John G A1 Sponga, Sandro A1 Makkar, Raj A1 Kini, Annapoorna S A1 Boukhris, Marouane A1 Gervais, Philippe A1 Linke, Axel A1 Crusius, Lisa A1 Holzhey, David A1 Rodés-Cabau, Josep K1 TAVI K1 TAVR K1 heart surgery K1 infective endocarditis AB Infective endocarditis (IE) following transcatheter aortic valve replacement (TAVR) has been associated with a dismal prognosis. However, scarce data exist on IE perivalvular extension (PEE) in such patients. This multicenter study included 579 patients who had the diagnosis of definite IE at a median of 171 (53-421) days following TAVR. PEE was defined as the presence of an intracardiac abscess, pseudoaneurysm, or fistula. A total of 105 patients (18.1%) were diagnosed with PEE (perivalvular abscess, pseudoaneurysm, fistula, or a combination in 87, 7, 7, and 4 patients, respectively). A history of chronic kidney disease (adjusted odds ratio [ORadj], 2.08; 95% confidence interval [CI]: 1.27-3.41; P = .003) and IE secondary to coagulase-negative staphylococci (ORadj, 2.71; 95% CI: 1.57-4.69; P  PEE occurred in about one-fifth of IE post-TAVR patients, with the presence of coagulase-negative staphylococci and chronic kidney disease determining an increased risk. Patients with PEE-IE exhibited high early and late mortality rates, and surgery during IE hospitalization seemed to be associated with better outcomes. YR 2022 FD 2022 LK http://hdl.handle.net/10668/19736 UL http://hdl.handle.net/10668/19736 LA en DS RISalud RD Apr 11, 2025