%0 Journal Article %A Panagides, Vassili %A Del Val, David %A Abdel-Wahab, Mohamed %A Mangner, Norman %A Durand, Eric %A Ihlemann, Nikolaj %A Urena, Marina %A Pellegrini, Costanza %A Giannini, Francesco %A Gasior, Tomasz %A Wojakowski, Wojtek %A Landt, Martin %A Auffret, Vincent %A Sinning, Jan Malte %A Cheema, Asim N %A Nombela-Franco, Luis %A Chamandi, Chekrallah %A Campelo-Parada, Francisco %A Munoz-Garcia, Erika %A Herrmann, Howard C %A Testa, Luca %A Kim, Won Keun %A Castillo, Juan Carlos %A Alperi, Alberto %A Tchetche, Didier %A Bartorelli, Antonio L %A Kapadia, Samir %A Stortecky, Stefan %A Amat-Santos, Ignacio %A Wijeysundera, Harindra C %A Lisko, John %A Gutiérrez-Ibanes, Enrique %A Serra, Vicenç %A Salido, Luisa %A Alkhodair, Abdullah %A Livi, Ugolino %A Chakravarty, Tarun %A Lerakis, Stamatios %A Vilalta, Victoria %A Regueiro, Ander %A Romaguera, Rafael %A Kappert, Utz %A Barbanti, Marco %A Masson, Jean Bernard %A Maes, Frédéric %A Fiorina, Claudia %A Miceli, Antonio %A Kodali, Susheel %A Ribeiro, Henrique B %A Mangione, Jose Armando %A Sandoli de Brito, Fabio %A Actis Dato, Guglielmo Mario %A Rosato, Francesco %A Ferreira, Maria Cristina %A Correia de Lima, Valter %A Colafranceschi, Alexandre Siciliano %A Abizaid, Alexandre %A Marino, Marcos Antonio %A Esteves, Vinicius %A Andrea, Julio %A Godinho, Roger R %A Alfonso, Fernando %A Eltchaninoff, Helene %A Søndergaard, Lars %A Himbert, Dominique %A Husser, Oliver %A Latib, Azeem %A Le Breton, Hervé %A Servoz, Clement %A Pascual, Isaac %A Siddiqui, Saif %A Olivares, Paolo %A Hernandez-Antolin, Rosana %A Webb, John G %A Sponga, Sandro %A Makkar, Raj %A Kini, Annapoorna S %A Boukhris, Marouane %A Gervais, Philippe %A Linke, Axel %A Crusius, Lisa %A Holzhey, David %A Rodés-Cabau, Josep %T Perivalvular Extension of Infective Endocarditis After Transcatheter Aortic Valve Replacement. %D 2022 %U http://hdl.handle.net/10668/19736 %X Infective endocarditis (IE) following transcatheter aortic valve replacement (TAVR) has been associated with a dismal prognosis. However, scarce data exist on IE perivalvular extension (PEE) in such patients. This multicenter study included 579 patients who had the diagnosis of definite IE at a median of 171 (53-421) days following TAVR. PEE was defined as the presence of an intracardiac abscess, pseudoaneurysm, or fistula. A total of 105 patients (18.1%) were diagnosed with PEE (perivalvular abscess, pseudoaneurysm, fistula, or a combination in 87, 7, 7, and 4 patients, respectively). A history of chronic kidney disease (adjusted odds ratio [ORadj], 2.08; 95% confidence interval [CI]: 1.27-3.41; P = .003) and IE secondary to coagulase-negative staphylococci (ORadj, 2.71; 95% CI: 1.57-4.69; P  PEE occurred in about one-fifth of IE post-TAVR patients, with the presence of coagulase-negative staphylococci and chronic kidney disease determining an increased risk. Patients with PEE-IE exhibited high early and late mortality rates, and surgery during IE hospitalization seemed to be associated with better outcomes. %K TAVI %K TAVR %K heart surgery %K infective endocarditis %~