TY  - JOUR
AU  - Torres, Sandra
AU  - Baulies, Anna
AU  - Insausti-Urkia, Naroa
AU  - Alarcón-Vila, Cristina
AU  - Fucho, Raquel
AU  - Solsona-Vilarrasa, Estel
AU  - Núñez, Susana
AU  - Robles, David
AU  - Ribas, Vicent
AU  - Wakefield, Leslie
AU  - Grompe, Markus
AU  - Lucena, M Isabel
AU  - Andrade, Raul J
AU  - Win, Sanda
AU  - Aung, Tin A
AU  - Kaplowitz, Neil
AU  - García-Ruiz, Carmen
AU  - Fernández-Checa, Jose C
PY  - 2019
DO  - 10.1053/j.gastro.2019.04.023
UR  - http://hdl.handle.net/10668/13884
T2  - Gastroenterology
AB  - Acetaminophen (APAP) overdose is a major cause of acute liver failure (ALF). Mitochondrial SH3BP5 (also called SAB) and phosphorylation of c-Jun N-terminal kinase (JNK) mediate the hepatotoxic effects of APAP. We investigated the involvement of...
LA  - en
KW  - APAP Toxicity
KW  - Lipid
KW  - Mouse Model
KW  - Signal Transduction
KW  - Acetaminophen
KW  - Adult
KW  - Animals
KW  - Chemical and Drug Induced Liver Injury
KW  - Disease Models, Animal
KW  - Drug Overdose
KW  - Endoplasmic Reticulum Stress
KW  - Hepatocytes
KW  - Humans
KW  - Lipogenesis
KW  - Liver
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Transgenic
KW  - Phosphoproteins
KW  - Steroids
KW  - Transplantation Chimera
KW  - Up-Regulation
KW  - Valproic Acid
TI  - Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure.
TY  - research article
VL  - 157
ER  -