RT Journal Article
T1 Prognostic Role of TAPSE to PASP Ratio in Patients Undergoing MitraClip Procedure.
A1 Trejo-Velasco, Blanca
A1 Estevez-Loureiro, Rodrigo
A1 Carrasco-Chinchilla, Fernando
A1 Fernández-Vázquez, Felipe
A1 Arzamendi, Dabit
A1 Pan, Manuel
A1 Pascual, Isaac
A1 Nombela-Franco, Luis
A1 Amat-Santos, Ignacio J
A1 Freixa, Xavier
A1 Hernández-Antolín, Rosa Ana
A1 Trillo-Nouche, Ramiro
A1 Andraka Ikazuriaga, Leire
A1 López-Mínguez, José R
A1 Sanmiguel Cervera, Dario
A1 Sanchis, Juan
A1 Diez-Gil, José Luis
A1 Ruiz-Quevedo, Valeriano
A1 Urbano-Carrillo, Cristóbal
A1 Becerra-Muñoz, Víctor Manuel
A1 Benito-González, Tomás
A1 Li, Chi Hion
A1 Mesa, Dolores
A1 Avanzas, Pablo
A1 Armijo, Germán
A1 Serrador-Frutos, Ana María
A1 Sanchis, Laura
A1 Lobán, Covadonga Fernández-Golfín
A1 Cid-Álvarez, Belén
A1 Hernández-García, José María
A1 Garrote-Coloma, Carmen
A1 Fernández-Peregrina, Estefanía
A1 Romero, Miguel
A1 León Arguero, Víctor
A1 Cruz-González, Ignacio
K1 MitraClip
K1 mitral valve regurgitation
K1 mitral valve repair
K1 pulmonary hypertension
K1 right ventricular to pulmonary arterial coupling
K1 transthoracic echocardiography
AB Transcatheter mitral valve repair (TMVR) is an effective therapy for high-risk patients with severe mitral regurgitation (MR) but heart failure (HF) readmissions and death remain substantial on mid-term follow-up. Recently, right ventricular (RV) to pulmonary arterial (PA) coupling has emerged as a relevant prognostic predictor in HF. In this study, we aimed to assess the prognostic value of tricuspid annular plane systolic excursion (TAPSE) to PA systolic pressure (PASP) ratio as a non-invasive measure of RV-to-PA coupling in patients undergoing TMVR with MitraClip (Abbott, CA, USA). Multicentre registry including 228 consecutive patients that underwent successful TMVR with MitraClip. The sample was divided in two groups according to TAPSE/PASP median value: 0.35. The primary combined endpoint encompassed HF readmissions and all-cause mortality. Mean age was 72.5 ± 11.5 years and 154 (67.5%) patients were male. HF readmissions and all-cause mortality were more frequent in patients with TAPSE/PASP ≤ 0.35: Log-Rank 8.844, p = 0.003. On Cox regression, TAPSE/PASP emerged as a prognostic predictor of the primary combined endpoint, together with STS-Score. TAPSE/PASP was a better prognostic predictor than either TAPSE or PASP separately. TAPSE/PASP ratio appears as a novel prognostic predictor in patients undergoing MitraClip implantation that might improve risk stratification and candidate selection.
SN 2077-0383
YR 2021
FD 2021-03-02
LK https://hdl.handle.net/10668/27035
UL https://hdl.handle.net/10668/27035
LA en
DS RISalud
RD Apr 5, 2025