RT Journal Article
T1 Antibiotic treatment for pneumonia complicating stroke: Recommendations from the pneumonia in stroke consensus (PISCES) group.
A1 Kishore, Amit K
A1 Jeans, Adam R
A1 Garau, Javier
A1 Bustamante, Alejandro
A1 Kalra, Lalit
A1 Langhorne, Peter
A1 Chamorro, Angel
A1 Urra, Xabier
A1 Katan, Mira
A1 Di-Napoli, Mario
A1 Westendorp, Willeke
A1 Nederkoorn, Paul J
A1 van-de-Beek, Diederik
A1 Roffe, Christine
A1 Woodhead, Mark
A1 Montaner, Joan
A1 Meisel, Andreas
A1 Smith, Craig J
K1 Stroke
K1 antibiotics
K1 post-stroke pneumonia
K1 stroke-associated pneumonia
K1 treatment
AB The microbiological aetiology of pneumonia complicating stroke is poorly characterised. In this second Pneumonia in Stroke ConsEnsuS statement, we propose a standardised approach to empirical antibiotic therapy in pneumonia complicating stroke, based on likely microbiological aetiology, to improve antibiotic stewardship. Systematic literature searches of multiple databases were undertaken. An evidence review and a round of consensus consultation were completed prior to a final multi-disciplinary consensus meeting in September 2017, held in Barcelona, Spain. Consensus was approached using a modified Delphi technique and defined a priori as 75% agreement between the consensus group members.Findings: No randomised trials to guide antibiotic treatment of pneumonia complicating stroke were identified. Consensus was reached for the following: (1) Stroke-associated pneumonia may be caused by organisms associated with either community-acquired or hospital-acquired pneumonia; (2) Treatment for early stroke-associated pneumonia ( Consensus recommendations for antibiotic treatment of the spectrum of pneumonia complicating stroke are proposed. However, there was limited evidence available to formulate consensus on choice of specific antibiotic class for pneumonia complicating stroke. Further studies are required to inform evidence-based treatment of stroke-associated pneumonia including randomised trials of antibiotics and validation of candidate biomarkers.
PB Sage Publications Ltd.
YR 2019
FD 2019-12
LK https://hdl.handle.net/10668/27765
UL https://hdl.handle.net/10668/27765
LA en
NO Kishore AK, Jeans AR, Garau J, Bustamante A, Kalra L, Langhorne P, et al. Antibiotic treatment for pneumonia complicating stroke: Recommendations from the pneumonia in stroke consensus (PISCES) group. Eur Stroke J. 2019 Dec;4(4):318-328.
DS RISalud
RD Apr 4, 2025