TY - JOUR AU - Diaz de la Guardia, Rafael AU - Velasco-Hernandez, Talia AU - Gutierrez-Aguera, Francisco AU - Roca-Ho, Heleia AU - Molina, Oscar AU - Nombela-Arrieta, Cesar AU - Bataller, Alex AU - Luis Fuster, Jose AU - Anguita, Eduardo AU - Vives, Susana AU - Zamora, Lurdes AU - Nomdedeu, Josep AU - Teresa Gomez-Casares, Maria AU - Ramirez-Orellana, Manuel AU - Lapillonne, Helene AU - Ramos-Mejia, Veronica AU - Carlos Rodriguez-Manzaneque, Juan AU - Bueno, Clara AU - Lopez-Millan, Belen AU - Menendez, Pablo PY - 2021 DO - 10.1182/bloodadvances.2020003958 SN - 2473-9529 UR - https://hdl.handle.net/10668/28398 T2 - Blood advances AB - Acute myeloid leukemia (AML) is the most common acute leukemia in adults. Disease heterogeneity is well documented, and patient stratification determines treatment decisions. Patient-derived xenografts (PDXs) from risk-stratified AML are crucial for... LA - en PB - Elsevier KW - AML biology and KW - testing novel KW - We characterize KW - human AML KW - Acute myeloid-leukemia KW - Mesenchymal stem-cells KW - Initiating cells KW - Xenotransplantation model KW - Myelodysplastic syndrome KW - Progenitor cells KW - Niche KW - Nucleophosmin KW - Frequency TI - Engraftment characterization of risk-stratified AML in NSGS mice TY - research article VL - 5 ER -