TY - JOUR AU - Leal-Lasarte, Magdalena AU - Mannini, Benedetta AU - Chiti, Fabrizio AU - Vendruscolo, Michele AU - Dobson, Christopher M AU - Roodveldt, Cintia AU - Pozo, David PY - 2021 DO - 10.1111/imm.13377 UR - http://hdl.handle.net/10668/17841 T2 - Immunology AB - Increasing evidence indicates that peripheral immune cells play a prominent role in neurodegeneration connected to protein misfolding, which are associated with formation of aberrant aggregates, including soluble protein misfolded oligomers. The... LA - en KW - Th1/Th17 KW - Tregs KW - immunoregulation KW - neurodegeneration KW - peripheral immunity KW - protein misfolding diseases KW - Adult KW - CD4-Positive T-Lymphocytes KW - Cell Differentiation KW - Cells, Cultured KW - Cytokines KW - Humans KW - Leukocytes, Mononuclear KW - Lymphocyte Activation KW - Middle Aged KW - Protein Folding KW - Proteostasis Deficiencies KW - T-Lymphocytes, Regulatory KW - Th1 Cells KW - Th17 Cells TI - Distinct responses of human peripheral blood cells to different misfolded protein oligomers. TY - research article VL - 164 ER -