TY - JOUR AU - Asenjo, Helena G. AU - Gallardo, Amador AU - López-Onieva, Lourdes AU - Tejada, Irene AU - Martorell-Marugán, Jordi AU - Carmona-Sáez, Pedro AU - Landeira, David PY - 2020 DO - 10.1126/sciadv.aay4768 UR - http://hdl.handle.net/10668/3496 T2 - Science Advances AB - When self-renewing pluripotent cells receive a differentiation signal, ongoing cell duplication needs to be coordinated with entry into a differentiation program. Accordingly, transcriptional activation of lineage specifier genes and cell... LA - en PB - American Association for the Advancement of Science (AAAS) KW - Polycomb Repressive Complex 2 KW - Mouse Embryonic Stem Cells KW - Pluripotent Stem Cells KW - Cell Cycle KW - Chromatin KW - Mice KW - Genes KW - Complejo Represivo Polycomb 2 KW - Células Madre Embrionarias de Ratones KW - Células Madre Pluripotentes KW - Ciclo Celular KW - Cromatina KW - Ratones KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Transformed KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus::Cell Nucleus Structures::Intranuclear Space::Chromosomes::Chromosome Structures::Chromatin KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains::Mice, Inbred C57BL KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Genetically Modified::Mice, Transgenic::Mice, Knockout KW - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Multiprotein Complexes::Polycomb-Group Proteins::Polycomb Repressive Complex 2 KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Gene Components::Regulatory Elements, Transcriptional::Promoter Regions, Genetic KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Protein Binding KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Protein Subunits KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Nucleotidyltransferases::RNA Nucleotidyltransferases::DNA-Directed RNA Polymerases::RNA Polymerase II KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression::Transcription, Genetic KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Developmental TI - Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells TY - research article ER -