TY  - JOUR
AU  - Couce, Alejandro
AU  - Rodríguez-Rojas, Alexandro
AU  - Blázquez, Jesús
PY  - 2016
DO  - 10.1534/genetics.115.185355
UR  - http://hdl.handle.net/10668/10085
T2  - Genetics
AB  - Any pathogen population sufficiently large is expected to harbor spontaneous drug-resistant mutants, often responsible for disease relapse after antibiotic therapy. It is seldom appreciated, however, that while larger populations harbor more mutants,...
LA  - en
KW  - antibiotic resistance cost
KW  - clonal heterogeneity
KW  - genetic diversity
KW  - mutation
KW  - population size
KW  - Anti-Bacterial Agents
KW  - Biological Evolution
KW  - Drug Resistance, Bacterial
KW  - Genetic Variation
KW  - Genotype
KW  - Humans
KW  - Models, Genetic
KW  - Mutation
KW  - Neoplasms
TI  - Determinants of Genetic Diversity of Spontaneous Drug Resistance in Bacteria.
TY  - research article
VL  - 203
ER  -