RT Journal Article
T1 Establishment of 2 control and 2 hPSC cell lines constitutively expressing the Notch ligand DLL4.
A1 González-Pozas, Federico
A1 Montes, Rosa
A1 Domingo-Reinés, Joan
A1 Ayllón, Verónica
A1 Ramos-Mejía, Verónica
AB The Notch ligand DLL4 has key roles during embryonic development of different tissues, but most of the data comes from animal models. Here we describe the generation and characterization of 2 human Pluripotent Stem Cell (hPSC) lines that overexpress DLL4, as well as the two corresponding control hPSC lines. DLL4 expression can be detected at the mRNA and protein level, and does not affect the pluripotency of the cells. These hPSC lines can be used to study the role of DLL4 during human embryonic development.
YR 2017
FD 2017-07-10
LK http://hdl.handle.net/10668/11915
UL http://hdl.handle.net/10668/11915
LA en
DS RISalud
RD Apr 18, 2025