TY - JOUR AU - Petkevicius, Kasparas AU - Virtue, Sam AU - Bidault, Guillaume AU - Jenkins, Benjamin AU - Çubuk, Cankut AU - Morgantini, Cecilia AU - Aouadi, Myriam AU - Dopazo, Joaquin AU - Serlie, Mireille J AU - Koulman, Albert AU - Vidal-Puig, Antonio PY - 2019 DO - 10.7554/eLife.47990 UR - http://hdl.handle.net/10668/14401 T2 - eLife AB - White adipose tissue (WAT) inflammation contributes to the development of insulin resistance in obesity. While the role of adipose tissue macrophage (ATM) pro-inflammatory signalling in the development of insulin resistance has been established, it is... LA - en KW - ER stress KW - adipose tissue KW - cell biology KW - fatty acid KW - human KW - human biology KW - immunometabolism KW - macrophage KW - medicine KW - membrane lipid KW - mouse KW - Adipose Tissue KW - Animals KW - Choline-Phosphate Cytidylyltransferase KW - Disease Models, Animal KW - Gene Deletion KW - Humans KW - Inflammation KW - Insulin Resistance KW - Macrophages KW - Mice, Obese KW - Obesity KW - Phosphatidylcholines TI - Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity. TY - research article VL - 8 ER -