TY - JOUR AU - Porteiro, Begoña AU - Fondevila, Marcos F AU - Delgado, Teresa C AU - Iglesias, Cristina AU - Imbernon, Monica AU - Iruzubieta, Paula AU - Crespo, Javier AU - Zabala-Letona, Amaia AU - Fernø, Johan AU - Gonzalez-Teran, Barbara AU - Matesanz, Nuria AU - Hernandez-Cosido, Lourdes AU - Marcos, Miguel AU - Tovar, Sulay AU - Vidal, Anxo AU - Sanchez-Ceinos, Julia AU - Malagon, Maria M AU - Pombo, Celia AU - Zalvide, Juan AU - Carracedo, Arkaitz AU - Buque, Xabier AU - Dieguez, Carlos AU - Sabio, Guadalupe AU - Lopez, Miguel AU - Aspichueta, Patricia AU - Martinez-Chantar, Maria L AU - Nogueiras, Ruben PY - 2017 DO - 10.1038/ncomms15111 UR - http://hdl.handle.net/10668/11180 T2 - Nature communications AB - p53 family members control several metabolic and cellular functions. The p53 ortholog p63 modulates cellular adaptations to stress and has a major role in cell maintenance and proliferation. Here we show that p63 regulates hepatic lipid metabolism.... LA - en PB - Nature Publishing Group KW - Adult KW - Animals KW - Endoplasmic reticulum stress KW - Fatty liver KW - Hepatocytes KW - Humans KW - I-kappa B kinase KW - Lipid metabolism KW - Liver KW - Male KW - Mice KW - Mice, inbred C57BL KW - Mice, Knockout KW - Middle aged KW - Phosphoproteins KW - Trans-activators KW - Transcription factors KW - Tumor suppressor proteins KW - X-box binding protein 1 TI - Hepatic p63 regulates steatosis via IKKβ/ER stress. TY - research article VL - 8 ER -