TY - JOUR AU - Ghenea, Simona AU - Chiritoiu, Marioara AU - Tacutu, Robi AU - Miranda-Vizuete, Antonio AU - Petrescu, Stefana Maria PY - 2022 DO - 10.1371/journal.pgen.1010069 UR - http://hdl.handle.net/10668/20413 T2 - PLoS genetics AB - EDEM-1, EDEM-2 and EDEM-3 are key players for the quality control of newly synthesized proteins in the endoplasmic reticulum (ER) by accelerating disposal and degradation of misfolded proteins through ER Associated Degradation (ERAD). Although many... LA - en KW - Animals KW - Caenorhabditis elegans KW - Endoplasmic Reticulum KW - Glycoproteins KW - Membrane Proteins KW - Protein Folding TI - Targeting EDEM protects against ER stress and improves development and survival in C. elegans. TY - research article VL - 18 ER -