TY - JOUR AU - Puerta-García, E AU - Urbano-Pérez, D AU - Carrasco-Campos, M I AU - Pérez-Ramírez, C AU - Segura-Pérez, A AU - Calleja-Hernández, AU - Cañadas-Garre, M PY - 2020 DO - 10.1016/j.suronc.2020.09.016 UR - http://hdl.handle.net/10668/16386 T2 - Surgical oncology AB - ABCB1, DPYD, MHTFR, XRCC1, ERCC1, GSTP1 and UGT1A1 genetic variants affect proteins related to CRC chemotherapy toxicity. A retrospective cohort study was conducted in 194 CRC patients. In first line treatment, DPYD rs17376848 AG genotype was... LA - en KW - COLORECTAL CANCER KW - Chemotherapy TREATMENT KW - Polymorphisms KW - TOXICITY KW - ATP Binding Cassette Transporter, Subfamily B KW - Aged KW - Antimetabolites, Antineoplastic KW - Antineoplastic Agents KW - Capecitabine KW - Colorectal Neoplasms KW - DNA-Binding Proteins KW - Dihydrouracil Dehydrogenase (NADP) KW - Endonucleases KW - Female KW - Fluorouracil KW - Genotype KW - Glutathione S-Transferase pi KW - Humans KW - Male KW - Methylenetetrahydrofolate Reductase (NADPH2) KW - Middle Aged KW - Oxaliplatin KW - Polymorphism, Genetic KW - Retrospective Studies KW - Spain KW - X-ray Repair Cross Complementing Protein 1 TI - Effect of DPYD, MTHFR, ABCB1, XRCC1, ERCC1 and GSTP1 on chemotherapy related toxicity in colorectal carcinoma. TY - research article VL - 35 ER -