RT Journal Article
T1 Prospective Multicentre Study on the Epidemiology and Current Therapeutic Management of Severe Bronchiolitis in Spain.
A1 Flores-Gonzalez, Jose C
A1 Mayordomo-Colunga, Juan
A1 Jordan, Iolanda
A1 Miras-Veiga, Alicia
A1 Montero-Valladares, Cristina
A1 Olmedilla-Jodar, Marta
A1 Alcaraz-Romero, Andrés J
A1 Eizmendi-Bereciartua, Miren
A1 Fernandez-Carrion, Francisco
A1 Santiago-Gutierrez, Carmen
A1 Aleo-Lujan, Esther
A1 Perez-Quesada, Sonia
A1 Yun-Castilla, Cristina
A1 Martin, Carmen
A1 Navarro-Mingorance, Alvaro
A1 Goñi-Orayen, Concha
K1 Administration, Inhalation
K1 Adrenal Cortex Hormones
K1 Anti-Bacterial Agents
K1 Bronchiolitis
AB Objective. To determine the epidemiology and therapeutic management of patients with severe acute bronchiolitis (AB) admitted to paediatric intensive care units (PICUs) in Spain. Design. Descriptive, prospective, multicentre study. Setting. Sixteen Spanish PICUs. Patients. Patients with severe AB who required admission to any of the participating PICUs over 1 year. Interventions. Both epidemiological variables and medical treatment received were recorded. Results. A total of 262 patients were recruited; 143 were male (54.6%), with median age of 1 month (0-23). Median stay in the PICU was 7 days (1-46). Sixty patients (23%) received no nebuliser treatment, while the rest received a combination of inhalation therapies. One-quarter of patients (24.8%) received corticosteroids and 56.5% antibiotic therapy. High-flow oxygen therapy was used in 14.3% and noninvasive ventilation (NIV) was used in 75.6%. Endotracheal intubation was required in 24.4% of patients. Younger age, antibiotic therapy, and invasive mechanical ventilation (IMV) were risk factors that significantly increased the stay in the PICU. Conclusions. Spanish PICUs continue to routinely use nebulised bronchodilator treatment and corticosteroid therapy. Despite NIV being widely used in this condition, intubation was required in one-quarter of cases. Younger age, antibiotic therapy, and IMV were associated with a longer stay in the PICU.
PB John Wiley & Sons
YR 2017
FD 2017-03-22
LK http://hdl.handle.net/10668/11111
UL http://hdl.handle.net/10668/11111
LA en
NO Flores-González JC, Mayordomo-Colunga J, Jordan I, Miras-Veiga A, Montero-Valladares C, Olmedilla-Jodar M, et al. Prospective Multicentre Study on the Epidemiology and Current Therapeutic Management of Severe Bronchiolitis in Spain. Biomed Res Int. 2017;2017:2565397
DS RISalud
RD May 13, 2025