TY - JOUR AU - Martín-Montañez, E AU - Pavia, J AU - Valverde, N AU - Boraldi, F AU - Lara, E AU - Oliver, B AU - Hurtado-Guerrero, I AU - Fernandez, O AU - Garcia-Fernandez, M PY - 2019 DO - 10.1016/j.freeradbiomed.2019.04.022 UR - http://hdl.handle.net/10668/13889 T2 - Free radical biology & medicine AB - Fingolimod is one of the few oral drugs available for the treatment of multiple sclerosis (MS), a chronic, inflammatory, demyelinating and neurodegenerative disease. The mechanism of action proposed for this drug is based in the phosphorylation of the... LA - en KW - Antioxidant KW - Fingolimod KW - Fingolimod phosphate KW - Mitochondria KW - Neuroprotection KW - Oxidative stress KW - Animals KW - Antioxidants KW - Cell Death KW - Cell Line KW - Dopaminergic Neurons KW - Fingolimod Hydrochloride KW - Humans KW - Lysophospholipids KW - Membrane Potential, Mitochondrial KW - Mice KW - Mitochondria KW - Molecular Mimicry KW - Multiple Sclerosis KW - Neuroprotection KW - Oxidative Stress KW - Oxygen Consumption KW - Phosphates KW - Reactive Oxygen Species KW - Sphingosine KW - Sphingosine-1-Phosphate Receptors KW - Vitamin K 3 TI - The S1P mimetic fingolimod phosphate regulates mitochondrial oxidative stress in neuronal cells. TY - research article VL - 137 ER -